Protein Info for H281DRAFT_03187 in Paraburkholderia bryophila 376MFSha3.1

Annotation: transcriptional regulator, LysR family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 334 PF00126: HTH_1" amino acids 4 to 62 (59 residues), 65.3 bits, see alignment E=3.9e-22 PF03466: LysR_substrate" amino acids 89 to 294 (206 residues), 136.3 bits, see alignment E=1e-43

Best Hits

KEGG orthology group: None (inferred from 94% identity to bge:BC1002_4411)

Predicted SEED Role

"Probable transcription regulator protein of MDR efflux pump cluster" in subsystem Multidrug Resistance Efflux Pumps

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MGK8 at UniProt or InterPro

Protein Sequence (334 amino acids)

>H281DRAFT_03187 transcriptional regulator, LysR family (Paraburkholderia bryophila 376MFSha3.1)
MDRLQAMQVFTRVVDTNSFTRAAETLDLPRASVTTIIQNLEAFLGTRLMHRTTRRLSLTP
DGAAYYERCVRILADVEETEASFQSGNKKPHGKLRIDMPGSIGRLLVIPQLCEFHTRYPD
IDLQLGLSDRQVDLLQEGVDCVVRVGALQDSSLVARRIGLFEGVTCAAPEYIERAGMPTS
LDDLENHKAVNYFSSRTGRTLDWAFMVDGKEVEVKMKGIVSVNDADAYVTCGLEGFGLIQ
PARFMVLPHLRSGQLVEVLPELKPLPMPISAVYPHSRHLSPKVRVFVDWIAEVFDRCPLL
SGRGALDATCSQRTLEERESAPALDTPIISEWVA