Protein Info for H281DRAFT_03059 in Paraburkholderia bryophila 376MFSha3.1

Annotation: two-component system, chemotaxis family, CheB/CheR fusion protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1046 PF01339: CheB_methylest" amino acids 10 to 187 (178 residues), 147.2 bits, see alignment E=1.3e-46 PF03705: CheR_N" amino acids 226 to 273 (48 residues), 43.6 bits, see alignment 5.9e-15 PF01739: CheR" amino acids 286 to 477 (192 residues), 171.3 bits, see alignment E=5.3e-54 PF13596: PAS_10" amino acids 738 to 844 (107 residues), 75.9 bits, see alignment E=9.9e-25 PF08448: PAS_4" amino acids 742 to 844 (103 residues), 26.2 bits, see alignment E=2.5e-09 PF07536: HWE_HK" amino acids 859 to 936 (78 residues), 60.8 bits, see alignment 5.2e-20

Best Hits

Predicted SEED Role

"Chemotaxis protein methyltransferase CheR (EC 2.1.1.80)" in subsystem Bacterial Chemotaxis (EC 2.1.1.80)

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.80

Use Curated BLAST to search for 2.1.1.80

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MMI9 at UniProt or InterPro

Protein Sequence (1046 amino acids)

>H281DRAFT_03059 two-component system, chemotaxis family, CheB/CheR fusion protein (Paraburkholderia bryophila 376MFSha3.1)
MAPATDFPIVGVGASAGAVEALEGFFRGLPQKPGLACVIVTHLSPDRESMLPEIVARFTD
MPVHAITDGMRIQTDNVYLLPSDAVVSVANRTLHVQEQDRSRRERKPIDIFLSTLAADVG
ELSAGVILSGADTDGTLGIKAIKERGGLTLAQASDGYGPHHADMPRSAIATGLVDFAVPA
EQMGGKLVNFAAGAFMLDGLDTLDERAAGPSGEGDASDFNEARNAIYAILRNQVGHDFSG
YKIKTFLRRVQRRMQVLEIETPDAYVARLTADPEEVAALFRDLLINVTSFFRDAPAFETL
ADTVLPKLLDGRGAEDTVRVWVPGCATGEEVYSIAMLLREQMEGRTAAPQVQIFATDIDD
GALGVARAARYPLPLLEGVSEERRRRFFVEDGSSYVLSKEVRDMCIFSPHSVIRDPPFSR
IDLVSCRNLLIYFGSEIQNQVIPTFHYALRPDGYLFLGTSENVSQFDELFTPVDKKHRIF
RRRADVAPQLRLPLTISALRIGQIASLTPTRPSLGSAGLRHVVDNHMLERFTPPHVLVTR
EGDVVYYSGRTGKYLEPAPGVPTRQLFALARKGLSLDLRSVFREAVESGRTVTRAGVVVE
GEGGRVQIISLTVEPLSEQVHGEHMYIVVFEDQGPGLAREEALARAQSMHDGTAVQFEKE
LRDTRERLQSMIEEYETALEELKSSNEELVSVNEELQSSNEELEASKEELVSLNEELHTV
NLELNGKIDALDRSNSDLQNLFESTSVATVFLDRNLVIRSFTPAMGGIFHIRPIDRGRPI
TELVSHLDLPGLELDIEAVFTTNQPRERQVSGKDGLSHFLVRLAPYRNGDRQTDGVVIAF
VEITGMVHAEERQEVLIAELQHRTRNLLAVIQSIAQQTLAGDSSLDTFTSRLAALGRLQG
LIGDANGNLIDLREIVRLELDALGVADSERIELRGPVVPLGFRNVQTIALVLHELATNAV
KYGALKDKEARLAVRWRVETELPGAASLVFDWIESGLRVAPDSTRTGFGRQLIEKALQFT
LGAKTALLFNADGVSCHIEIPMPAVH