Protein Info for H281DRAFT_02977 in Paraburkholderia bryophila 376MFSha3.1

Annotation: diguanylate cyclase (GGDEF) domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 395 transmembrane" amino acids 44 to 65 (22 residues), see Phobius details amino acids 71 to 91 (21 residues), see Phobius details amino acids 100 to 121 (22 residues), see Phobius details amino acids 127 to 145 (19 residues), see Phobius details amino acids 154 to 173 (20 residues), see Phobius details amino acids 179 to 197 (19 residues), see Phobius details TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 214 to 383 (170 residues), 162.2 bits, see alignment E=4.6e-52 PF00990: GGDEF" amino acids 218 to 380 (163 residues), 141.4 bits, see alignment E=1.1e-45

Best Hits

KEGG orthology group: None (inferred from 54% identity to rme:Rmet_5041)

Predicted SEED Role

"GGDEF domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (395 amino acids)

>H281DRAFT_02977 diguanylate cyclase (GGDEF) domain-containing protein (Paraburkholderia bryophila 376MFSha3.1)
MKNIIAPLPAEFDIHPLRVEFRNKDVERNFQAHHLPRNQATLRTTLVFCSFFYLAFALTD
ASVLGYTSETLLLFFARMFVAVTAMTGLYLARTRPASSAVLQLAATAAEIVGMGTFMLIV
QHRPGEIPWHAMSFSIMLIVVYVFIPNRLIVSQTIAFSATALFIIVVSSMLTLRFSDMLT
MSMLLLLTNSFGLVAARRYHRLWRDEYRVRALLTDQAMKDHLTGCYNRRHLHDVLLPTEL
KRAQRHRLSFAVILCDIDHFKSINDTFGHLCGDAVLQNCSAVLHNCVRRQVDCVVRYGGE
EFLLLLPEMDKTDAVRLAERLRLSCAQTPIEVGGQSVAVTASFGVLAVDLTSGDAEVTEE
AIIAAADKLLYRAKTEGRNNIQADSLLDGRGRRPV