Protein Info for H281DRAFT_02779 in Paraburkholderia bryophila 376MFSha3.1

Annotation: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 122 PF00072: Response_reg" amino acids 5 to 112 (108 residues), 81.7 bits, see alignment E=2.3e-27

Best Hits

Swiss-Prot: 33% identical to CHEY_LISIN: Chemotaxis protein CheY (cheY) from Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262)

KEGG orthology group: None (inferred from 92% identity to bgf:BC1003_3670)

Predicted SEED Role

"Chemotaxis protein CheC -- inhibitor of MCP methylation" in subsystem Bacterial Chemotaxis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MI85 at UniProt or InterPro

Protein Sequence (122 amino acids)

>H281DRAFT_02779 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain (Paraburkholderia bryophila 376MFSha3.1)
MPLPVLVVDDSTLARKLLIRSLPEGWDIEITQASDGAAALDLYRAGKAAVMFLDLTMPVM
NGFQVLEAIQHEGLDTFVIVVSADVQSGAVERAKALGAIGFVAKPVSPEAIRPILAEYGL
HE