Protein Info for H281DRAFT_02771 in Paraburkholderia bryophila 376MFSha3.1

Annotation: Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 738 transmembrane" amino acids 520 to 542 (23 residues), see Phobius details amino acids 567 to 596 (30 residues), see Phobius details amino acids 601 to 623 (23 residues), see Phobius details amino acids 648 to 669 (22 residues), see Phobius details amino acids 676 to 698 (23 residues), see Phobius details amino acids 710 to 730 (21 residues), see Phobius details PF00614: PLDc" amino acids 160 to 185 (26 residues), 30 bits, see alignment (E = 5.5e-11) amino acids 382 to 407 (26 residues), 31.4 bits, see alignment (E = 2.1e-11) PF13091: PLDc_2" amino acids 294 to 421 (128 residues), 46.6 bits, see alignment E=4.5e-16 PF09335: SNARE_assoc" amino acids 583 to 697 (115 residues), 82.7 bits, see alignment E=4.7e-27

Best Hits

KEGG orthology group: None (inferred from 92% identity to bgf:BC1003_3660)

Predicted SEED Role

"Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MJF0 at UniProt or InterPro

Protein Sequence (738 amino acids)

>H281DRAFT_02771  Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase (Paraburkholderia bryophila 376MFSha3.1)
MSEPDPIESDLLDAPSPSPSRDTADAPPAVPNGEVMDTRTTCEWILKAHRASVLIDAASY
YAVLREMIPRARHSIFILGWDIDSRIELVPGGVDDGFPPKLSEFLCAVLDANPQLRIYLL
GWDFAMLYAFEREWLPSYKPAWHAHRRLWFRLDGRHPLGASHHQKIVVIDDSLAFTGGID
LTGSRWDTPEHRPDDPLRKNLGKTSYEPMHDAQLMFDGPAAAAIAHLARERWRRSRRSSK
AGRPFNGKPPPRTDLWPSRIEPDFADIDLGISLTEPAYDGRPAIQQVKALHLATVAAARR
NIYVENQYFTANSVGSALQKRIAEENGPDLAVVCPYRQSGWLQEATMGVLRARLHKLLEA
ADRNGRYAMYAPAVDAPNGRFINVHSKIMIADDRLLVIGSANLNNRSMVLDSECCIVIDA
RDNPLRQAAIARIRNRLLAEHLDSSEADVEQALARHGRLNAAIASLKGHSARTLVPLTPE
VPPELRDIADRVHVLDPEAPIEANELLAQFLPEPTRRPVIAKLLVLGALALGVVALTIAW
RFTPFGHELTFAKLTADAQRLAATHFGPIAVVAMYAVAALLSVPVTLLIAVTGLVFGAVA
GAAYALAGTLIAAAAGWAAGAWLGRDAVRELAGERLNQLSERLRSKGLVAMILLRLVPVA
PFSIVNLAAGASHIRFWDFMAGTAIGMAPGVVLATSFARQLVTALTHPTPLSLLLVAAIG
VALVSMSLVLRRVLMRRQ