Protein Info for H281DRAFT_02710 in Paraburkholderia bryophila 376MFSha3.1

Annotation: transcriptional regulator, Crp/Fnr family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 252 PF00027: cNMP_binding" amino acids 29 to 116 (88 residues), 81.2 bits, see alignment E=6.9e-27 PF13545: HTH_Crp_2" amino acids 149 to 218 (70 residues), 44.1 bits, see alignment E=2.4e-15 PF00325: Crp" amino acids 184 to 207 (24 residues), 24.4 bits, see alignment (E = 2.8e-09)

Best Hits

KEGG orthology group: K01420, CRP/FNR family transcriptional regulator, anaerobic regulatory protein (inferred from 72% identity to bgd:bgla_2g25100)

Predicted SEED Role

"transcriptional regulator, Crp/Fnr family" in subsystem Oxidative stress

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MI34 at UniProt or InterPro

Protein Sequence (252 amino acids)

>H281DRAFT_02710 transcriptional regulator, Crp/Fnr family (Paraburkholderia bryophila 376MFSha3.1)
MWFVGKSELLSLIQCHCLDEVMPAFSDHRTLRKNTVIYRPDESSEHVYLLKSGSVRLYRL
TEDGQEITLAFVKAGMIFGDGDVLNEDSYSHHAQALTPSMVCYIRKADFKELLARYDVIN
QFVLRNHYLRWQEAQQLIENLSLHDVRKRLVNILVMFSGQVGTPFDHPEHGDTVLIDLPI
AQDKLAEFIGTSRESVNRHFSDLKSEGFVDMHERKIVLTPAFVARYITKAPAFAALPANP
APREFRAPLMRA