Protein Info for H281DRAFT_02692 in Paraburkholderia bryophila 376MFSha3.1

Annotation: nudix-type nucleoside diphosphatase, YffH/AdpP family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 199 TIGR00052: nudix-type nucleoside diphosphatase, YffH/AdpP family" amino acids 9 to 189 (181 residues), 147.3 bits, see alignment E=1.9e-47 PF00293: NUDIX" amino acids 48 to 152 (105 residues), 22.6 bits, see alignment E=4.6e-09

Best Hits

Swiss-Prot: 60% identical to NUDK_PECAS: GDP-mannose pyrophosphatase NudK (nudK) from Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)

KEGG orthology group: None (inferred from 90% identity to bmu:Bmul_3674)

MetaCyc: 52% identical to GDP-mannose hydrolase (Escherichia coli K-12 substr. MG1655)
3.6.1.-

Predicted SEED Role

"Nudix hydrolase family protein YffH" in subsystem Nudix proteins (nucleoside triphosphate hydrolases)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (199 amino acids)

>H281DRAFT_02692 nudix-type nucleoside diphosphatase, YffH/AdpP family (Paraburkholderia bryophila 376MFSha3.1)
MSATKDRVRIVESTTLSDDWYTLKKVTFDFLRRDGTWQRQSRETYDRGNGATILLHNRRT
GNVVLTRQFRMPVFVNGHDGMLIEAAAGLLDMATPEERIRLEAEEETGYRVSNIRKVFEA
YMSPGSVTEKLYFYLGEYDASTRVNDGGGIEDEGEDLEVLEMPLGTALQLVRSGEIVDGK
TIMLLQHLALSEIAEAGRA