Protein Info for H281DRAFT_02674 in Paraburkholderia bryophila 376MFSha3.1

Annotation: carbon-monoxide dehydrogenase medium subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00941: FAD_binding_5
  • amino acids 5 to 175 (171 residues), 136 bits, E=1.2e-43
• PF03450: CO_deh_flav_C
  • amino acids 185 to 284 (100 residues), 75.3 bits, E=3.7e-25

Best Hits

KEGG orthology group: K03519, carbon-monoxide dehydrogenase medium subunit [EC: 1.2.99.2] (inferred from 48% identity to bav:BAV2738)

Predicted SEED Role

"Carbon monoxide dehydrogenase medium chain (EC 1.2.99.2)" in subsystem CO Dehydrogenase (EC 1.2.99.2)

KEGG Metabolic Maps

• Methane metabolism
• Trinitrotoluene degradation

Isozymes

Compare fitness of predicted isozymes for: 1.2.99.2

Use Curated BLAST to search for 1.2.99.2

Sequence Analysis Tools

See A0A2Z5MI80 at UniProt or InterPro

Protein Sequence (293 amino acids)

>H281DRAFT_02674 carbon-monoxide dehydrogenase medium subunit (Paraburkholderia bryophila 376MFSha3.1)
MKPSEFLYHAPTTLDEAVQLLGTLEDARVLAGGQSLMPMMNFRYLMTSHLIDLNGVEALT
RIEQRGDRLHIGAMARQRDIELSPLVIQRAPLIREAYQLVSHKQIRNRGTLGGSLCQLDP
SSEQPCFTAALDGVLTIARYEDGAVTHRELPMSDWAVMYMTPALEEGELLAGISLDIWPE
GHGYAFEEFARRHGDYAIVGVAALCTADAQGNLDRVSLTICGVAPGPVRMHDVETALRGR
PMDDAALRMASDAASALDVMTDAHVSTDYRQHLAGVLTERALKRAFSRVARQS