Protein Info for H281DRAFT_02659 in Paraburkholderia bryophila 376MFSha3.1

Annotation: LysR family transcriptional regulator, cyn operon transcriptional activator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 294 PF00126: HTH_1" amino acids 3 to 61 (59 residues), 89.1 bits, see alignment E=1.4e-29 PF03466: LysR_substrate" amino acids 87 to 290 (204 residues), 159.8 bits, see alignment E=6.2e-51

Best Hits

KEGG orthology group: K11921, LysR family transcriptional regulator (inferred from 73% identity to bpy:Bphyt_2145)

Predicted SEED Role

"Cyn operon transcriptional activator" in subsystem Cyanate hydrolysis or DNA-binding regulatory proteins, strays

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (294 amino acids)

>H281DRAFT_02659 LysR family transcriptional regulator, cyn operon transcriptional activator (Paraburkholderia bryophila 376MFSha3.1)
MLLRHIRYFLAVAEHRNFTRAAEALHVSQPTLSQQIRQLEDTLCVQLLDRSGRTIRLTDA
GAAWLLYAQRALQDLDAGRRAIHDVHDLSRGSLRLGMTPTFTAYLVGPLVDRFNQRYPGI
ILNIEEMSQERMEVLLNEDELDMGIAFADTHSPDIETESLLVEALAVVVGNSHPRARKRG
ALTPRDFEREAWVLLNETFATRHYIDHYCREHGVAPRIAVEANSISAVIGIVGCSQLATI
LPAAIARQNGDLSLLKLEPSLPQRTAALLRRKGAYRTAAARAFAEVATEVSQSL