Protein Info for H281DRAFT_02602 in Paraburkholderia bryophila 376MFSha3.1

Annotation: DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 224 PF00072: Response_reg" amino acids 4 to 113 (110 residues), 102.9 bits, see alignment E=1.1e-33 PF00486: Trans_reg_C" amino acids 147 to 218 (72 residues), 59.2 bits, see alignment E=3.6e-20

Best Hits

Swiss-Prot: 39% identical to BASR_ECOLI: Transcriptional regulatory protein BasR (basR) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 92% identity to bug:BC1001_3887)

Predicted SEED Role

"Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MP38 at UniProt or InterPro

Protein Sequence (224 amino acids)

>H281DRAFT_02602 DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain (Paraburkholderia bryophila 376MFSha3.1)
MKLLLVEDNTELAHWIAHLLRLENFAVDSVPDGECADMVLTTQRYDVVVLDLRLPRMDGK
EVLARLRRRGDRVPVIMLTAHGSTDDKVDCFSTGADDYVVKPFDARELVARIKALIRRQS
GDMTSCLACGDLRYICDTREFFHNDARLALRRREHTVLETLMLRKGKTVSKSALMESVFC
LDDEPSADAIDIYIHRLRKHLANCSAQITTLRGLGYILRPQAIE