Protein Info for H281DRAFT_02390 in Paraburkholderia bryophila 376MFSha3.1

Annotation: F-type H+-transporting ATPase subunit a

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 274 transmembrane" amino acids 33 to 51 (19 residues), see Phobius details amino acids 87 to 105 (19 residues), see Phobius details amino acids 137 to 156 (20 residues), see Phobius details amino acids 207 to 227 (21 residues), see Phobius details amino acids 243 to 267 (25 residues), see Phobius details TIGR01131: ATP synthase F0, A subunit" amino acids 21 to 269 (249 residues), 134 bits, see alignment E=3.9e-43 PF00119: ATP-synt_A" amino acids 34 to 267 (234 residues), 186.2 bits, see alignment E=3.9e-59

Best Hits

Swiss-Prot: 69% identical to ATP6_JANMA: ATP synthase subunit a (atpB) from Janthinobacterium sp. (strain Marseille)

KEGG orthology group: K02108, F-type H+-transporting ATPase subunit a [EC: 3.6.3.14] (inferred from 98% identity to bug:BC1001_3526)

Predicted SEED Role

"ATP synthase F0 sector subunit a"

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.14

Use Curated BLAST to search for 3.6.3.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MFJ9 at UniProt or InterPro

Protein Sequence (274 amino acids)

>H281DRAFT_02390 F-type H+-transporting ATPase subunit a (Paraburkholderia bryophila 376MFSha3.1)
MDPSEYIAHHLQNFSTGHQTSIFDIHVWNLDTLFWSIVCGLATIFILHMAARKATSGVPG
RFQCAIEMLVEMVEDQSKSMIHGTRTFIAPLALTVFVWVALMNALDFIPVDLPGHVIGWL
GLSEVIPHHRIVPTADLNGTLGIALGVFALMIYYNFKIKGAGGFVHELLSAPFGAHPLLW
IPNLALNIIEFVAKTVSLGMRLFGNMYAGELLFLLIALLGSIWSFGADTTVLGFIGHVIA
GSVWAIFHILIVLLQAFIFMMLTLVYIGQAHDTH