Protein Info for H281DRAFT_02381 in Paraburkholderia bryophila 376MFSha3.1

Annotation: amino acid/amide ABC transporter substrate-binding protein, HAAT family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 386 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF13458: Peripla_BP_6" amino acids 26 to 365 (340 residues), 162.6 bits, see alignment E=3.3e-51 PF01094: ANF_receptor" amino acids 57 to 225 (169 residues), 66.5 bits, see alignment E=3.4e-22

Best Hits

KEGG orthology group: K01999, branched-chain amino acid transport system substrate-binding protein (inferred from 97% identity to bug:BC1001_3535)

Predicted SEED Role

"Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MF94 at UniProt or InterPro

Protein Sequence (386 amino acids)

>H281DRAFT_02381 amino acid/amide ABC transporter substrate-binding protein, HAAT family (Paraburkholderia bryophila 376MFSha3.1)
MTKTKQWVRTGIAMALMCGASAAIAQVKIGVTLSTTGPAASLGIPEKNTIALLPKEIGGK
TVQYIILDDASDTGKAVQNTRKLIDEDHVDAIIGSTVTPNSLAMLDPASEGKTPVISLAA
SAAIISPMDAKRAWAFKPPQNDSLMADAIADYMEHHGVKTVGFIGFADAYGDSWNNVFTA
AANAHNLKIVSNERFNRTDASVTGQVLKTMGANPDAVLIAGSGTPSALPAKTLKERGYKG
KVYQTHGVANNDFLRVCAKDCEGEILPAGPILVADQLPESNPVKKSSLAYKAAYEKAYGA
GSVATFGGHAWDAGQMLQRAIPEALKTAQPGTEAFRVALRSALESIKELPVSHGIMNTTT
TDHNGLDKRARVIVQIVDGKWKLQND