Protein Info for H281DRAFT_02122 in Paraburkholderia bryophila 376MFSha3.1

Annotation: indolepyruvate ferredoxin oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1195 transmembrane" amino acids 734 to 751 (18 residues), see Phobius details amino acids 885 to 905 (21 residues), see Phobius details PF01558: POR" amino acids 739 to 923 (185 residues), 64.6 bits, see alignment E=1.4e-21 PF20169: DUF6537" amino acids 954 to 1153 (200 residues), 187.8 bits, see alignment E=2.4e-59

Best Hits

KEGG orthology group: K04090, indolepyruvate ferredoxin oxidoreductase [EC: 1.2.7.8] (inferred from 87% identity to bph:Bphy_0143)

Predicted SEED Role

"Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits" in subsystem Aromatic amino acid interconversions with aryl acids

Isozymes

Compare fitness of predicted isozymes for: 1.2.7.8

Use Curated BLAST to search for 1.2.7.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5M774 at UniProt or InterPro

Protein Sequence (1195 amino acids)

>H281DRAFT_02122 indolepyruvate ferredoxin oxidoreductase (Paraburkholderia bryophila 376MFSha3.1)
MTARLPIDGTPALSDYKLSDNLTATRGRIFLTGTQALVRLALMQRSLDRARGMNTAGFIS
GYRGSPLGMVDQQLWKAKKLLSASDIRFLPAINEELGGTAVLGTQRVEADPERTVEGVFA
MWYGKGPGVDRAGDALKHGNAYGSSPHGGVLVVAGDDHGCVSSSMPHQSDFAMMAWHMPV
VNPSNIADMLEFGLYGWALSRFSGAWVGYKAISETVESGSTVDLDALRTDWSAPEDFEAP
SGGLHNRWPDLPSLTIESRMHAKLDAVRHFAKTNSIDKWIAPSPHANVGIVTCGKAHLDL
METLRRLDLTVADLDAAGVRIYKVGLSFPLEMMRIDTFVEGLSEVLVIEEKGPVIEQQIK
DYLYNRTQGARPAVIGKQAQDGSMLLSSLGELRPSRILPVFANWLAKHKPALDRRERVVD
LVAPQILSNAADSVKRTPYFCSGCPHNTSTKVPEGSIAHAGIGCHFMASWMERDTTGLIQ
MGGEGVDWASHSMFTKTRHVFQNLGDGTYFHSGILAIRQAVAAKATITYKILYNDAVAMT
GGQPVDGSISVPQIARQVEAEGVSRFVVVSDEPEKYDGHHDLFPKGTTFHHRSEMDTVQR
ELRDTDGVTVLIYDQTCAAEKRRRRKKGEFPDPDKRLFINEEVCEGCGDCGVQSNCLSVE
PVETALGRKRRIDQSSCNKDYSCVNGFCPSFVTVEGGKLKKAAGAAFDPQALAERINALR
LPATQLDAAPYDILVTGVGGTGVVTVGALISMAAHLEGKSASVLDFMGFAQKGGSVLSFV
RFAARDEWLNQVRIDTQQADVLLACDMVVGASADALQTVRHGRTRIVVNTHAIPNATFVQ
NPDATLHADALIDKMRHAAGAERMSTCDAQALATRFLGDTIGANILMLGYAWQLGLVPVS
FGALMRAIELNNVAVQMNQLAFSIGRLAAEDPAALESLWQARHAAKQTVRIDTLDELIAH
REGRLQIYGGASYVKRYRALVDAARRAESAIGANSERVTRAVATTFYRLLAVKDEYEVAR
LHTDAAFREALEAQFEGVAGKDFGINFNLAPPALTRAHSGANPTKKTFGQWMWPVLGVLA
KVRGLRGTMLDPFGRTLERKMEHELADDYETTLQRALAKLNADNLDDVAKLADLHARVRG
YGHVKLANLAGVKRGERDLAARLQIEAATGTSVKKSLEEVKGAGQLRGIPVVVAK