Protein Info for H281DRAFT_02121 in Paraburkholderia bryophila 376MFSha3.1

Annotation: inward rectifier potassium channel

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 320 transmembrane" amino acids 59 to 83 (25 residues), see Phobius details amino acids 95 to 112 (18 residues), see Phobius details amino acids 123 to 146 (24 residues), see Phobius details PF07885: Ion_trans_2" amino acids 69 to 148 (80 residues), 41.6 bits, see alignment E=1.4e-14 PF17655: IRK_C" amino acids 155 to 310 (156 residues), 99.8 bits, see alignment E=2.2e-32

Best Hits

Swiss-Prot: 41% identical to IRK10_MAGMG: Inward rectifier potassium channel Kirbac3.1 from Magnetospirillum magnetotacticum

KEGG orthology group: K08715, inward rectifier potassium channel (inferred from 88% identity to bug:BC1001_0144)

Predicted SEED Role

"Kef-type K+ transport systems, predicted NAD-binding component"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5M9D0 at UniProt or InterPro

Protein Sequence (320 amino acids)

>H281DRAFT_02121 inward rectifier potassium channel (Paraburkholderia bryophila 376MFSha3.1)
MATEPSDRFARIGREKVSAENSPSRGSRELRLDDRVVIAHGMPTRFWQDLYHRALVVRWP
MFFVSLAVIFLLLNTTFAALYMLGNASIANQYPPGFGGAFFFSVETLATVGYGDMHPQTV
YAHWIATLEIFVGMSSIALATGLIFARFSRPHAKIMFARYAIIRPLDGHMTLMVRSANGR
QNVIAEAHARLRIMRRETTPEGYTLRKLYDLTLVRDQHPVFKLGWSIMHVIDETSPLFGE
TAETLKASDTSLLLTLEGVDESTSQTMQARHMWTCDQIYWQHRFVDIMSERDGVSHIDYS
HFDEIVPLDEAPVRAAVSNV