Protein Info for H281DRAFT_02118 in Paraburkholderia bryophila 376MFSha3.1

Annotation: fructokinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 303 PF00294: PfkB" amino acids 26 to 294 (269 residues), 154.4 bits, see alignment E=2.2e-49

Best Hits

KEGG orthology group: K00847, fructokinase [EC: 2.7.1.4] (inferred from 95% identity to bgf:BC1003_0173)

Predicted SEED Role

"Fructokinase (EC 2.7.1.4)" in subsystem Fructose utilization or Mannitol Utilization or Ribitol, Xylitol, Arabitol, Mannitol and Sorbitol utilization or Sucrose utilization or Sucrose utilization Shewanella (EC 2.7.1.4)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.4

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5M7Q3 at UniProt or InterPro

Protein Sequence (303 amino acids)

>H281DRAFT_02118 fructokinase (Paraburkholderia bryophila 376MFSha3.1)
MSHVSNELPVFVSAGDILTDLVRTGASQWLSRPGGAGWNVARCVARLGLPTACAGSLGVD
NFSDELWDASVAAGLDMRFMQRVERPPLLAIVHRTHPPAYFFMGENGADLAFDPAHLPAG
WMQQVKWAHFGCISLVRQPLGDTLAALAAELRSRGVKISFDPNYRNLMEHGYEPTLRKMA
ALADLIKVSDEDLRLLFKTDDEAHALAQLRAMNPAATVLVTRGPETAVLIDGAATFEARP
PRVEVVDTVGAGDASIGGLLFSLMTASQRAWPEHLAFALAAGAAACRHAGAHAPSLDEVV
ALL