Protein Info for H281DRAFT_02117 in Paraburkholderia bryophila 376MFSha3.1
Annotation: Mannose or cellobiose epimerase, N-acyl-D-glucosamine 2-epimerase family
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: None (inferred from 95% identity to bgf:BC1003_0174)Predicted SEED Role
"D-mannose isomerase (EC 5.3.1.7)" in subsystem Mannose Metabolism (EC 5.3.1.7)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 5.3.1.7
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A2Z5M776 at UniProt or InterPro
Protein Sequence (427 amino acids)
>H281DRAFT_02117 Mannose or cellobiose epimerase, N-acyl-D-glucosamine 2-epimerase family (Paraburkholderia bryophila 376MFSha3.1) MTLSATPPSANGAPVVPAVASFRSREFLLSHVEDTLRFYAPNVFDSSGGFFHFFRDDGSV YDKTTRHLVSSCRYVFNYAMAYRQFGDPKHLEYARHGLQFLRDAHWDGQHEGYDWEIEWS DGRKRTLDATRHCYGLAFVLLAYSHAAMAGIEEAKPMIGATFELMEHRFWDAAAGLYADE ASPEWRVSSYRGQNANMHTTEALLAAHEATGHLVYLDRAERVASNITLRQAKLSQGLVWE HFHADWSVDWHYNEEDSSNIFRPWGFQPGHQTEWAKLLLILERYRPLPWLLPRAIELFDA AMTHAWDEDHGGLYYGFGPDGTVCDHDKYFWVQAETFATAALLGKRTGNERFWDWYDEIW RYSWAHFVDHKYGAWYRILTCDNRKYSDEKSPAGKTDYHTMGACYEVLTHALADGSTAAA VSTEHAK