Protein Info for H281DRAFT_02061 in Paraburkholderia bryophila 376MFSha3.1
Annotation: phospholipid/cholesterol/gamma-HCH transport system permease protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K02066, putative ABC transport system permease protein (inferred from 97% identity to bug:BC1001_0219)Predicted SEED Role
"ABC-type transport system involved in resistance to organic solvents, permease component USSDB6A"
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A2Z5M8K4 at UniProt or InterPro
Protein Sequence (389 amino acids)
>H281DRAFT_02061 phospholipid/cholesterol/gamma-HCH transport system permease protein (Paraburkholderia bryophila 376MFSha3.1) MAATPITTLQRSLNYDTPPGLEVAAGSQGKIVRLSGQWTALALARDRATGHVIPQLRSLE GAEGIGQWDLSRIDRMDHVGGQALWRVWGHRMPPDTELTDTQRDIFERIALLDTVRETAE PVVRFDPFTRLGLGLFSFFEHLYGGVAMLGRVVLDLLAIARKPALTPWTEISANIYNAGT RALPITALVAFLIGIVLSYLSAQQLRLFGANQYIVNILGLSVIRELGPVLSAILVAGRSG SAITAQIGVMRVTEELDAMRVMGIPHGLRLILPRVVALGVAMPLLVMWTNIIALSGGALA AKIVLGIDMSYFARALPGVVPAANLWIGLGKGVVFGMLIAIVGCHFGFRIKANSQSLGEG TTTSVVTSITIVILADAVFAILFQNVGLG