Protein Info for H281DRAFT_01979 in Paraburkholderia bryophila 376MFSha3.1

Annotation: N-acetylglucosamine 6-phosphate deacetylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00221: N-acetylglucosamine-6-phosphate deacetylase
  • amino acids 37 to 360 (324 residues), 266.3 bits, E=2.1e-83
• PF01979: Amidohydro_1
  • amino acids 41 to 350 (310 residues), 62.1 bits, E=5.7e-21

Best Hits

KEGG orthology group: K01443, N-acetylglucosamine-6-phosphate deacetylase [EC: 3.5.1.25] (inferred from 98% identity to bug:BC1001_0283)

Predicted SEED Role

"N-acetylglucosamine-6-phosphate deacetylase (EC 3.5.1.25)" in subsystem Chitin and N-acetylglucosamine utilization or Sialic Acid Metabolism or UDP-N-acetylmuramate from Fructose-6-phosphate Biosynthesis (EC 3.5.1.25)

MetaCyc Pathways

• N-acetylglucosamine degradation II (3/3 steps found)
• N-acetylglucosamine degradation I (2/2 steps found)
• superpathway of N-acetylneuraminate degradation (16/22 steps found)
• peptidoglycan recycling I (10/14 steps found)
• D-galactosamine and N-acetyl-D-galactosamine degradation (1/4 steps found)
• superpathway of N-acetylglucosamine, N-acetylmannosamine and N-acetylneuraminate degradation (2/6 steps found)
• N-acetyl-D-galactosamine degradation (1/5 steps found)
• chitin derivatives degradation (3/8 steps found)

KEGG Metabolic Maps

• Aminosugars metabolism
• Galactose metabolism
• Nucleotide sugars metabolism

Isozymes

Compare fitness of predicted isozymes for: 3.5.1.25

Use Curated BLAST to search for 3.5.1.25

Sequence Analysis Tools

See A0A2Z5M7J4 at UniProt or InterPro

Protein Sequence (367 amino acids)

>H281DRAFT_01979 N-acetylglucosamine 6-phosphate deacetylase (Paraburkholderia bryophila 376MFSha3.1)
MLTGNILTTDGWIHGTLEFENGRITAITGERVDPATNDAPYILPGFIDLHVHGGGGADVM
EAGNAIETITRTHARYGTTSLLATTMTAPRDELMSVVAGLGDVARVRTPGCSRVLGVHLE
GPYINPGKLGAQPDAAVSAVMDEVLKYLSIAPIRVVTLAPEIAGHMDIISEMAARGVRVQ
LGHSLGTYDDAVAALKHGACGFTHLFNAMSPLHHRNPGLVGAALAHAEFAEIIPDLLHVH
PGAIRAALRAIPRLYVVTDSTSATGMPDGEYRLGSQHVTKCLGGVRLADGTLAGSTLTMD
QALRNLVSIGLPIADVSNRLSRYAADYLGIEDRGRIARGAWADVVVFDRELALSATYVEG
EAIVEYA