Protein Info for H281DRAFT_01933 in Paraburkholderia bryophila 376MFSha3.1

Annotation: A/G-specific DNA-adenine glycosylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 382 signal peptide" amino acids 18 to 19 (2 residues), see Phobius details transmembrane" amino acids 20 to 38 (19 residues), see Phobius details TIGR01084: A/G-specific adenine glycosylase" amino acids 33 to 303 (271 residues), 351.5 bits, see alignment E=1.8e-109 PF00730: HhH-GPD" amino acids 63 to 195 (133 residues), 84.4 bits, see alignment E=1.1e-27 PF00633: HHH" amino acids 126 to 155 (30 residues), 38.4 bits, see alignment (E = 1e-13) PF14815: NUDIX_4" amino acids 265 to 375 (111 residues), 83.8 bits, see alignment E=1.2e-27

Best Hits

KEGG orthology group: K03575, A/G-specific adenine glycosylase [EC: 3.2.2.-] (inferred from 88% identity to bug:BC1001_0305)

Predicted SEED Role

"A/G-specific adenine glycosylase (EC 3.2.2.-)" in subsystem DNA repair, bacterial (EC 3.2.2.-)

Isozymes

Compare fitness of predicted isozymes for: 3.2.2.-

Use Curated BLAST to search for 3.2.2.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (382 amino acids)

>H281DRAFT_01933 A/G-specific DNA-adenine glycosylase (Paraburkholderia bryophila 376MFSha3.1)
MPSRLTPKSGPRSAPSAAPAVSAVPASALTSGFAARLIAWQRMHGRHDLPWQNTRNAYRI
WLSEIMLQQTQVSTVIPYYAKFLARFPDVAALAAAPVDDVMALWAGLGYYTRARNLHRCA
QAVVERHGGAFPASVDELAELPGIGRSTAAAIASFAFGARATILDGNVKRVLARVFGVEG
FPGEKKVENAMWTLAESLLPSNASDDEVSAYTQGLMDLGATLCVRGKPDCLRCPFSADCV
ANVTGRQRELPAARPKKAVPTRRTWMLVLRDGDAVMLEKRPPSGIWGGLWSLPEAADEAA
LATRAREFGGDGAVSPLAPLTHVFTHFKLEIEPRLAEFDRSVGALAALRDADTAWVSVSD
LDSFGVPAPVRKLLESLRGSLI