Protein Info for H281DRAFT_01884 in Paraburkholderia bryophila 376MFSha3.1

Annotation: two-component system, chemotaxis family, CheB/CheR fusion protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1058 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF01339: CheB_methylest" amino acids 10 to 187 (178 residues), 149 bits, see alignment E=4.3e-47 PF03705: CheR_N" amino acids 222 to 267 (46 residues), 36.8 bits, see alignment (E = 9e-13) PF01739: CheR" amino acids 280 to 470 (191 residues), 162.3 bits, see alignment E=3.4e-51 PF13596: PAS_10" amino acids 732 to 838 (107 residues), 78 bits, see alignment E=2.7e-25 PF08448: PAS_4" amino acids 736 to 839 (104 residues), 26.6 bits, see alignment E=2.2e-09 PF07536: HWE_HK" amino acids 853 to 930 (78 residues), 58.1 bits, see alignment 4.3e-19

Best Hits

Predicted SEED Role

"Chemotaxis protein methyltransferase CheR (EC 2.1.1.80)" in subsystem Bacterial Chemotaxis (EC 2.1.1.80)

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.80

Use Curated BLAST to search for 2.1.1.80

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1058 amino acids)

>H281DRAFT_01884 two-component system, chemotaxis family, CheB/CheR fusion protein (Paraburkholderia bryophila 376MFSha3.1)
MTRPTTFPIVGIGASAGAVEALEGFFRGMPRNPGLACVIVTHLSPDRDSMLPEIVARFTD
MPVHAIADGTSIEPNNVYLLPTDAVVSVEDRTLHVQSQDKIRRERKPIDVFFSTLAADVG
ELSAGVILSAADSDGTLGIKAIKERGGLTLAQAGDGFGPHHPDMPRSAIATGLVDFVVPA
EVMGQKLASFAAGVFMLDGFAGKSGAQTNASEFDEARTAIYAILRSQVGHDFSGYKVNTF
VRRVQRRMQVLEILTPEAYVARLSKEPEEVAALFRDLLINVTSFFRDAQAFEALAEIVIP
QLLEGRGADDTIRVWVPGCATGEEVYSIAMLLREQMDGRQPAPRVQIFATDIDDGALAVA
RAARYPLAMLDGVSDERRERFFIRDGSSYVLTKEVRDFCIFSPHSVIRDPPFSRIDLVSC
RNLLIYFGTEIQNQAIPTFHYALRPDGYLFLGTSENVSQFDELFLPVEKKHRIFRRRADV
SPQIRVPLSVSSLKIGQPGGLTPSRPALGGAALRHVVDNHMLERFTPPHVLVTRDGDVVY
YSGRTGKYLEAAPGVPTRQLFALARKGLSLDLRSVFRETVESGRTVTREGVVVEGEDGRV
QLISLTVEPLTGQPQDEHMYLVIFEDEGPLAAREEALARAQSMHDGTAAQIEKELRETRE
RLQSMIEEYETALEELKSSNEELVSVNEELQSSNEELEASKEELVSLNEELQTVNMELSG
KIDALDRSNSDLRNLFESTSVATVFLDRNLVIRSFTPAMDSIFHIRAIDRGRPITELVSR
LELHGLEHDIETVFKMNQPRERHVSGRDGLAHFLVRLAPYRNGDRQIDGVVIAFVDVTDM
VHAEDRQNVLIGELQHRTRNLLAVIQSIAEQTLTADQKLETFTSRLAALGRLQGLVGEAD
GNLINLSDIVRLEFDALGVANGERVKINGPVVPLGFRNIQIIALVLHELATNALKYGALK
DEQARLDVRWRVEAGTAEAALLVFEWVESGVRVRPDSSRTGFGRQLIEKALKFTLQARTE
LTFNADGISCHIEIPLPAAGSAGGNASNATPSQQSRTR