Protein Info for H281DRAFT_01876 in Paraburkholderia bryophila 376MFSha3.1

Annotation: outer membrane protein, multidrug efflux system

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 494 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details TIGR01845: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family" amino acids 18 to 467 (450 residues), 412.4 bits, see alignment E=1.3e-127 PF02321: OEP" amino acids 66 to 258 (193 residues), 87.1 bits, see alignment E=6.6e-29 amino acids 282 to 464 (183 residues), 89.4 bits, see alignment E=1.3e-29

Best Hits

KEGG orthology group: None (inferred from 75% identity to bge:BC1002_5537)

Predicted SEED Role

"RND efflux system, outer membrane lipoprotein CmeC" in subsystem Multidrug Resistance Efflux Pumps or Multidrug efflux pump in Campylobacter jejuni (CmeABC operon)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (494 amino acids)

>H281DRAFT_01876 outer membrane protein, multidrug efflux system (Paraburkholderia bryophila 376MFSha3.1)
MRTTHFASVGVVLLTGLASLSLTGCLLGPDYARPKVDVPATFRFSIQDTADTANTAWWEQ
FGDPVLNDLIAAALADNLDVKIAAARVEEFRGQFVTTRSGLFPQVGANFNASRQRATLSG
GVPLPANVNPVYNQFDASVSAAWEIDLFGKTRRETEAARANLLASEEGRRGTILSLVASV
ASSYINLRSLDRQLDIAKATVESRAESVKVFTLRFAGGEVSQMELAQSQSEYQAALATIP
ELETQIGVQEDALAVLLGRNPEPILRGHDLDALTAPAIPSSLPSELLERRPDVLQAEQNL
VAQNALIGAARALYFPSISLTGLFGSVSTQFSNLFTGPARVWSFAGAVSLPIFTAGNIEG
QVHQAEARQQEALFAYQKAIQVAFQEVADALIALQKSREQLGIQQDQVTALSSYSHLARL
RYEGGYTSYIEVLDAERSLFNAQLSYTQTQGAELTSFVRLYKAMGGGWVVKAEEMTQPPA
PQPMAGVPAGEAPR