Protein Info for H281DRAFT_01769 in Paraburkholderia bryophila 376MFSha3.1

Annotation: PAS domain S-box-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 639 TIGR00229: PAS domain S-box protein" amino acids 28 to 138 (111 residues), 69.8 bits, see alignment E=1.2e-23 amino acids 139 to 266 (128 residues), 84.6 bits, see alignment E=3.1e-28 PF13426: PAS_9" amino acids 28 to 130 (103 residues), 54.4 bits, see alignment E=4.7e-18 amino acids 156 to 258 (103 residues), 50.7 bits, see alignment E=6.6e-17 PF00989: PAS" amino acids 28 to 128 (101 residues), 39.4 bits, see alignment E=1.9e-13 amino acids 144 to 256 (113 residues), 41.6 bits, see alignment E=4.1e-14 PF08448: PAS_4" amino acids 28 to 132 (105 residues), 44.2 bits, see alignment E=7.3e-15 amino acids 156 to 261 (106 residues), 30.6 bits, see alignment E=1.2e-10 PF08447: PAS_3" amino acids 40 to 123 (84 residues), 27.2 bits, see alignment E=1.4e-09 PF02518: HATPase_c" amino acids 389 to 506 (118 residues), 70.7 bits, see alignment E=4.8e-23 PF00072: Response_reg" amino acids 524 to 634 (111 residues), 58.7 bits, see alignment E=2.2e-19

Best Hits

KEGG orthology group: None (inferred from 60% identity to nmu:Nmul_A2015)

Predicted SEED Role

"diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)" in subsystem Bacterial hemoglobins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MKH3 at UniProt or InterPro

Protein Sequence (639 amino acids)

>H281DRAFT_01769 PAS domain S-box-containing protein (Paraburkholderia bryophila 376MFSha3.1)
MTNFAPSPGDVSGEESFQLLVAGVRDYAIFMLDAEGYIKTWNAGAQRFKGYAPREILGQH
FSVFYTDSDRAGGRPALALRTARDEGKFEDEGWRVRKDGSQFWASVVIDPLRDDSGKLIG
FAKITRDITDRKMAQEALRESEEQFRLLVQGVTDYAIYMLSPAGEVTNWNVGAERIKGYT
REEILGKHFSCFYTDEDRASGLPALTLSTAAAEGRAEREGWRVRKDGSRFWAHVVVDAIR
NGAGELVGFAKVTRDVTERKQAAEALERANAALFQSQKMESLGQLTGGVAHDFNNLLAVM
SNGLDVLSLRVQDHADLKMLETMQRAVARGATLTQQLLSFARQQPLKVERCNLNAVIRGF
EAVLRRAGNSTIELEIRPEPRPRPVLLDVARFEAALLNLIVNARDAMPAGGKIAITVENV
EVREGTVGSLVEGPYVKVSVADTGSGMPPEVAARAFEPFFTTKEVGKGTGLGLSQVYGFI
SQSGGDVLIRSEPDMGTVVSMYLPIANSASGDADSLAGPTLDTVLVVEDEPDLLDATAAL
FRSLGYEVLTASNGAEAMNALGRRDDIRVLFTDVVMPKGIDGIQLARSTRDRHPEIRIVL
ASGYPLPALKAQHGNLDDFAFIHKPYRLADLVRTLGMAT