Protein Info for H281DRAFT_01765 in Paraburkholderia bryophila 376MFSha3.1

Annotation: cytochrome c oxidase subunit I+III

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 663 transmembrane" amino acids 56 to 77 (22 residues), see Phobius details amino acids 98 to 122 (25 residues), see Phobius details amino acids 135 to 154 (20 residues), see Phobius details amino acids 183 to 207 (25 residues), see Phobius details amino acids 220 to 248 (29 residues), see Phobius details amino acids 271 to 292 (22 residues), see Phobius details amino acids 304 to 327 (24 residues), see Phobius details amino acids 338 to 363 (26 residues), see Phobius details amino acids 374 to 397 (24 residues), see Phobius details amino acids 413 to 434 (22 residues), see Phobius details amino acids 446 to 471 (26 residues), see Phobius details amino acids 491 to 509 (19 residues), see Phobius details amino acids 601 to 618 (18 residues), see Phobius details amino acids 624 to 642 (19 residues), see Phobius details TIGR02891: cytochrome c oxidase, subunit I" amino acids 45 to 550 (506 residues), 702.8 bits, see alignment E=1.2e-215 PF00115: COX1" amino acids 53 to 499 (447 residues), 500.3 bits, see alignment E=2.4e-154

Best Hits

Swiss-Prot: 41% identical to COX1_COREF: Cytochrome c oxidase subunit 1 (ctaD) from Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)

KEGG orthology group: K02274, cytochrome c oxidase subunit I [EC: 1.9.3.1] (inferred from 78% identity to bxe:Bxe_C0080)

Predicted SEED Role

"Cytochrome c oxidase polypeptide I (EC 1.9.3.1)" in subsystem Terminal cytochrome C oxidases (EC 1.9.3.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.9.3.1

Use Curated BLAST to search for 1.9.3.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MM22 at UniProt or InterPro

Protein Sequence (663 amino acids)

>H281DRAFT_01765 cytochrome c oxidase subunit I+III (Paraburkholderia bryophila 376MFSha3.1)
MADLAPDTPDLRLARRPEIGRMPQGSPREQRLRELWESEPGWRGWLSTVDHKQIGLRYIV
TAFVFLIAGGIEALIMRVQLARPNAHLLSPEQYDQLFTMHGITMIFLYALPVLSGFSNYL
WPLVLGARDMAFPRLNALSFWVFLFAGIFLYASFPLGQAPNAGWFNYVPLANLEYNTGPN
IDVYALGMVLLGVSTTVGSVNFVVTLLRMRAPGMSIDRLPILVWGTLTASAANLVAVPAV
SLAFLMLWLDRQIGTHFFDVTHGGRPMLWQHMFWMFAHPWVYVVVLPAMGIVSDALPTFC
RRPLVGYTPVAISTVATMMIGFVVWIHHMFATGIGPLALAFFGAASTLISIPSAVATFAW
IATIWLGRPVYRVPFLFFAGFVLMFVIGGVSGVMTAAVPFDWQLTDTYFVVAHLHYVLLG
INVFPVLGGIYYWFPKFTGRMTSERLGKLSFWVTFVGFNVGFFPMHISGLLGMPRRVYTY
PANMGWDTTNMITTIGAFIFALGILIFLIDMAVSLRRGAPAGDNPWDGASLEWSVPSPPP
PYNFAVVPVVASRNPLWEDRIGEGSNSKLDEGFLLDHGREALGTTPLDARPDIILKMPTD
SYAPFLLGLFSALLFVAMLLRTWIFAGAMVAACGAAILLWLWPERLLIQREPEPVRDAGA
GHE