Protein Info for H281DRAFT_01734 in Paraburkholderia bryophila 376MFSha3.1

Annotation: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 498 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details TIGR01845: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family" amino acids 16 to 471 (456 residues), 400.4 bits, see alignment E=5.6e-124 PF02321: OEP" amino acids 72 to 262 (191 residues), 66.1 bits, see alignment E=1.9e-22 amino acids 287 to 469 (183 residues), 94.4 bits, see alignment E=3.9e-31

Best Hits

KEGG orthology group: None (inferred from 96% identity to bgf:BC1003_2091)

Predicted SEED Role

"Heavy metal RND efflux outer membrane protein, CzcC family" in subsystem Cobalt-zinc-cadmium resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MMF3 at UniProt or InterPro

Protein Sequence (498 amino acids)

>H281DRAFT_01734 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family (Paraburkholderia bryophila 376MFSha3.1)
MLTLLHPFARRSAAIVTACALTACSTLPTYHQPEAAVPTQYAGAAAPGWSVAAPADAKPP
GPWWTLFHDAELDQLEARVDVSNQTVAKAVAQLQAARAMLDYQRAGYAPTVTAGAAQSRT
RLSQNVLGHSLAGQTVPDYSVGATASWEPDLFGRVKDATVYARDNAQASEADLQAVRLSV
ASDLATDYFDLRSLDRQKKLLDDSVTAYAAALSIVQQQLKDGAIDASAVAQAQTQLESTR
SQDTDIDVQRAQLQHAIATLIGMPASSFALASEVKSVGLPQIPTGVPSQLLERRPDIAAA
ERRVAAANAQIGEARAAYYPNLTLSATAGLESTFFAPWLTAPSLFWSLGAQLAGTLFDGG
RRDASLKGANAQYDSAVADYRQTVLTAFQQVEDNLSTLTTLASEADSQQRATSAAELSLK
LTTNRYQAGAVSYLDVVTAQTIALTNERTQELIDARRVDASVQLLKALGGGWSRNSLDES
GNAAATTPPNSPSTRPQT