Protein Info for H281DRAFT_01642 in Paraburkholderia bryophila 376MFSha3.1

Annotation: penicillin amidase (EC 3.5.1.11). Cysteine peptidase. MEROPS family C59

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 359 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF02275: CBAH" amino acids 28 to 315 (288 residues), 151.3 bits, see alignment E=5.1e-48 PF03417: AAT" amino acids 36 to 206 (171 residues), 29.5 bits, see alignment E=5.5e-11

Best Hits

KEGG orthology group: K01442, choloylglycine hydrolase [EC: 3.5.1.24] (inferred from 86% identity to bpy:Bphyt_6641)

Predicted SEED Role

"Choloylglycine hydrolase (EC 3.5.1.24)" (EC 3.5.1.24)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.1.24

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (359 amino acids)

>H281DRAFT_01642 penicillin amidase (EC 3.5.1.11). Cysteine peptidase. MEROPS family C59 (Paraburkholderia bryophila 376MFSha3.1)
MRRPFSAVVTCFAAAATPLVDPAASLACTRVVYLGDNDDVITARSMDWKLDVATNLYILP
RGIARTGESGPNSLKWTAKYGSVVATGYDVSTTDGMNEKGLAAQLLWLVESQYPPFDKNS
KPGLTIAAWAQYVLDNFATVSEAVAALEKEPFTIVTDNVPGEQRLTTLHLAMSDATGDSA
IVEYIGGKQIIHHGRQYQVMTNSPTFDEQLALNEYWKQIGGTVWLPGTNRSADRFARASF
YVNAIPKSEDPAIALASVFSVIRNASVPFGITTPGEPNISSTRWRTVADHKRMLYFFESA
LTPSTFWVDLKKVDFSAAAPVKRLDLGKDQRNTFGGEVSKDFQRAPAFPFLGIDASKSR