Protein Info for H281DRAFT_01512 in Paraburkholderia bryophila 376MFSha3.1

Annotation: transcriptional regulator, IclR family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 274 TIGR02431: beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family" amino acids 24 to 269 (246 residues), 358 bits, see alignment E=1.1e-111 PF09339: HTH_IclR" amino acids 31 to 78 (48 residues), 49.7 bits, see alignment 2.6e-17 PF01614: IclR" amino acids 143 to 267 (125 residues), 123.9 bits, see alignment E=3.8e-40

Best Hits

Swiss-Prot: 44% identical to PCAR_PSEPU: Pca regulon regulatory protein (pcaR) from Pseudomonas putida

KEGG orthology group: K02624, IclR family transcriptional regulator, pca regulon regulatory protein (inferred from 97% identity to bgf:BC1003_4153)

Predicted SEED Role

"Transcriptional regulator, IclR family" in subsystem Homogentisate pathway of aromatic compound degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MJM4 at UniProt or InterPro

Protein Sequence (274 amino acids)

>H281DRAFT_01512 transcriptional regulator, IclR family (Paraburkholderia bryophila 376MFSha3.1)
MSKAPPPSPDVSASAEPAPDKPGDSYVQSFARGLAVIRAFDATRPEQTLTDVAAATGLTR
AGARRILLTLQTLGYVEAEGRLFRLTPKILDLGFAYLTSMPFWNLAEPVMEELSAQVHES
CSAAVLDRTEIVYVLRVPTHKIMTINLSIGSRLPAYCTSMGRVLLSALDDETLETTLNSS
PLYAHTPRTVTDKEELKKLIAQVRRQGWAIVDQELEGGLISLSAPIRNRQGRVIAAMNIS
GNAQRNSARQMVKAFLEPLQQAAQTVSEMVARRG