Protein Info for H281DRAFT_01459 in Paraburkholderia bryophila 376MFSha3.1

Annotation: type VI secretion system secreted protein VgrG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1244 transmembrane" amino acids 1141 to 1155 (15 residues), see Phobius details TIGR03361: type VI secretion system Vgr family protein" amino acids 2 to 525 (524 residues), 314.2 bits, see alignment E=1.5e-97 TIGR01646: Rhs element Vgr protein" amino acids 4 to 529 (526 residues), 307.6 bits, see alignment E=1.8e-95 PF05954: Phage_GPD" amino acids 10 to 356 (347 residues), 201.9 bits, see alignment E=2.9e-63 PF13296: T6SS_Vgr" amino acids 506 to 609 (104 residues), 115 bits, see alignment E=3.6e-37 PF10106: DUF2345" amino acids 644 to 791 (148 residues), 125.6 bits, see alignment E=3.2e-40

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1244 amino acids)

>H281DRAFT_01459 type VI secretion system secreted protein VgrG (Paraburkholderia bryophila 376MFSha3.1)
MLAVRSVRGREAVGELFEYVVVAESQTALLLNPTDATQIDLTQTVGTDGTVAIEISGIGT
FIAGQPGDIGRSNIGADVRYINGEIVSARIQCVEDRAAVYEFVLRPFIWRATQNSDSRIF
SGTVVDILQKVFGRYLGPVDWRIGGPWNGMRRYPMRDMVRQAWESDWTFALRLMEEWGLV
FWFEHAKDRHTLVVSDTSGGFHRHGIAYEELRFHTGGRIDEEHISSLAVTHTVTAGKACV
NDHDYMRPRLRRSNAPNRHTYEAAGGTADPSIEIYAPAEFAQPDTFPSSYPHDAREEGQY
LARVKVEATRCKGLRAKGTGRLRGLQPGRTFRLVNYPHDSANREYLVLACELDISEVGTS
TSAWRTYAVAAEFELHPVGEYYRLPQLTPKPRVEGYEYAVIVAPQGREMWIDSRNRLLIQ
FDWDREARFDGATSIWVRVVTQWQGSELGVVTPGRAGQMVVVSHVHGDPDRPVVAGFVAD
RFNTPPWELPANAALSGIRSKSLDHGAQSNHLALDDTAGKLQAQLASDHAKSSLSLGHIT
RIDGNKGRQDARGEGFELRSDRWGVLRASMGLLFTSWGRSGAAGKVKDMDETHARLTEAR
SIHEELALSAQQHGAQQATGAQRDVAKALGDANAALRGRASDSAHDFPEFGQPDIAVSSA
ANLHAAAQDNTHIVSGKHTALTAGGNVAIAALKSLFASVREAIAFYASKSITMIAATGHI
HLEARTDGLQAIAREDVTVTSQNGWLRLAALKGIEINAGGTLLRLTPQGVTVHTNGHYLV
HAASHATDDPQAAPVMLPVTQENPGRLAAHHVLVEDGGGFILGGQPYRITLDDGQVIEGV
TNGRGEMQVATSNAVSFGLVELMSQSEPDKVISASTTTVWRDDSLPTPETVEMPEKRTTK
VGGKSAETPGEGLTGDGKPPVFVGCDPMNWGLRTCHPLRNAKGADTPPAFQYRSDIEYPV
AKSYTAAVKESLCRIEWASLAGKTDEDLAAVIVPAIQGPIWNALQAGPFGLPERVAKQGG
AMPNIVIVSASNAAEYSFPIGAHGVFQGSKWVLCLSRWDIDEIIRSVKGVPETNVTLIDF
ADTVYHEARHCQQLFWQIALLSAFPDDYREFSDMRECFKQIAGKKIFDLACATPFPNDSL
ARAGIHAMLVFYYYWVITKTKGIADGQFIQADLEKVEAEVCKVRNVTPEQARTMAVTYTS
YLHEQDAFLCGEVVKYCWIGRSQLRNPGTCTSAYAHVIQSIGAH