Protein Info for H281DRAFT_01450 in Paraburkholderia bryophila 376MFSha3.1

Annotation: transcriptional regulator, LacI family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 transmembrane" amino acids 55 to 75 (21 residues), see Phobius details PF00356: LacI" amino acids 3 to 48 (46 residues), 56.6 bits, see alignment 3.5e-19 PF00532: Peripla_BP_1" amino acids 62 to 276 (215 residues), 55.8 bits, see alignment E=1e-18 PF13407: Peripla_BP_4" amino acids 158 to 278 (121 residues), 38.8 bits, see alignment E=1.7e-13 PF13377: Peripla_BP_3" amino acids 172 to 331 (160 residues), 117.6 bits, see alignment E=1.2e-37

Best Hits

KEGG orthology group: K02529, LacI family transcriptional regulator (inferred from 90% identity to bxe:Bxe_B2079)

Predicted SEED Role

"Transcriptional regulators"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MJ30 at UniProt or InterPro

Protein Sequence (350 amino acids)

>H281DRAFT_01450 transcriptional regulator, LacI family (Paraburkholderia bryophila 376MFSha3.1)
VATLKDVAALAGVGMSTASRVISGKGPVSADAASRVRAAIEQLNFRPSSIGRAMATQSLG
MIGIFVPTFFGSYYGTILKQTDTELRAVRRHVVVATGCGEVSPREQAIEAVRFLIGRDCD
GVVVISHDLHDEDLIMLHRMHPKMVFLNRAFDQVPEASFCADHRYGGELAARTLLEHGHR
DIAVISGPFTASDNLTRLEGFFAELERAGISRSDVTLIESDFSPEGGYAAAQKLLDSKRR
YTGLFCANDTMAVSALARFHEAGISVPDELSVIGYDDDYSAAYTAPGLTSVHIPTAELTQ
NAVRWLLNQCYRTTWEIFREFPVSVTTRESVGPAPGAKPASISASCFGGA