Protein Info for H281DRAFT_01447 in Paraburkholderia bryophila 376MFSha3.1

Annotation: Threonine/homoserine/homoserine lactone efflux protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 212 transmembrane" amino acids 12 to 32 (21 residues), see Phobius details amino acids 44 to 62 (19 residues), see Phobius details amino acids 68 to 93 (26 residues), see Phobius details amino acids 120 to 145 (26 residues), see Phobius details amino acids 154 to 178 (25 residues), see Phobius details amino acids 190 to 208 (19 residues), see Phobius details PF01810: LysE" amino acids 20 to 210 (191 residues), 121.2 bits, see alignment E=2e-39

Best Hits

KEGG orthology group: None (inferred from 86% identity to bpy:Bphyt_5879)

Predicted SEED Role

"L-lysine permease" in subsystem Lysine degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (212 amino acids)

>H281DRAFT_01447 Threonine/homoserine/homoserine lactone efflux protein (Paraburkholderia bryophila 376MFSha3.1)
MTPTAFLTADVLIAYSAYFVGTASPGPSNLAIMSLAMSAGRRSALTFALGVVSGSFFWAL
LASLGLSAVLATCSECLAAIKVAGGIYLLWLGVKSARSAFAPRAMPASEARRNEPLTRLY
LRGLLLHLTNPKAVLVWMSIVSLAMSPAGGTSHIAPIVLGCMCIGASVFSSYALLFSTAS
ARRVYVAIRRWLDGSLAIMFGIAGLKMLTSKS