Protein Info for H281DRAFT_01442 in Paraburkholderia bryophila 376MFSha3.1

Annotation: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 512 signal peptide" amino acids 1 to 32 (32 residues), see Phobius details TIGR01845: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family" amino acids 21 to 478 (458 residues), 377 bits, see alignment E=6.5e-117 PF02321: OEP" amino acids 75 to 269 (195 residues), 65.4 bits, see alignment E=3e-22 amino acids 296 to 461 (166 residues), 88.3 bits, see alignment E=2.9e-29

Best Hits

KEGG orthology group: None (inferred from 86% identity to bgf:BC1003_4118)

Predicted SEED Role

"Heavy metal RND efflux outer membrane protein, CzcC family" in subsystem Cobalt-zinc-cadmium resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MJJ5 at UniProt or InterPro

Protein Sequence (512 amino acids)

>H281DRAFT_01442 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family (Paraburkholderia bryophila 376MFSha3.1)
VKLTRGSRGVVRIAAAVGAAASAAMLAACTAGPDYKRPQAEVPPEWKTDSYWRVAAPSHA
PMDPDWWNVYRDSTLATLETQALAQNQTLVAASAHYAQAKATLANTRAQQVPEVDLAATA
SRFRISRDRPRTNYGVPTTSTVQNNLQIGPTISYDTDLFGRIRRQVEGATASAEQSADDL
ANARLVLTTEVASDYFSLRELDTEIDVLNQSVTLQQKALDYVNSEHELGAVSGLDVLQQK
SLLDTTRVQAQLLLNQRAQFEHALAALVGVPAPQFAIEPKVLNFQVPAIALGVPSDVLQR
RPDIASAERAMAAANAQIGVAKAAFFPSLTLTPGIGWESTQFASLLSAPTLMWTLGAAAS
QVLFDGGRRAANVQFASEGYKATEADYRQTVLNAFQQVQDGITGLAVLDGAAKQSEQAVA
DSQRLLALANDRYSGGLVAYLDVITAQQSLLNSKRQDAQIRGQQMTLSVSLVKALGGGWD
ATTGPASGESRVGQQDMQPEGAGPVQTRAAAQ