Protein Info for H281DRAFT_01395 in Paraburkholderia bryophila 376MFSha3.1

Annotation: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 523 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details TIGR01845: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family" amino acids 20 to 475 (456 residues), 342 bits, see alignment E=2.8e-106 PF02321: OEP" amino acids 72 to 241 (170 residues), 74.4 bits, see alignment E=5.3e-25 amino acids 291 to 473 (183 residues), 73.7 bits, see alignment E=8.6e-25

Best Hits

KEGG orthology group: None (inferred from 90% identity to bgf:BC1003_4106)

Predicted SEED Role

"RND efflux system, outer membrane lipoprotein CmeC" in subsystem Multidrug Resistance Efflux Pumps or Multidrug efflux pump in Campylobacter jejuni (CmeABC operon)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MIZ6 at UniProt or InterPro

Protein Sequence (523 amino acids)

>H281DRAFT_01395 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family (Paraburkholderia bryophila 376MFSha3.1)
MKLATSSRLRLVSASIVVSMGVALSGCISVGPDFREPDVTLENQWLESLPPAAQSTPAGE
AAWWKAFNDPVLSALEQRAYERNLSLQVAGLHIFKARAQLAISGENLLPQSGSASVGASH
INTSGVGPIPPAHLWAEHLHVNAGWEIDFWGKYRRQIESDRAQLRVSEAAYDNALVSMFA
DVANAYIDLRALEQRIAVARQNLKSVQDSLTLTQARYKRGASSQLDVEQAATLVAETEAQ
IPPLIKARVQDRDTLAVLLADPPDAVDAQLKGSTAIPVPPTQIDVGIPADLLRRRPDVRQ
AALNAAAQSALIGAAKAKLYPSLSLTGLFGLSSGEQHGIGLTQWGGKTIGLFSAGISLPI
LDRAQLQNAVRIQDAAFQEAVLDYQNTVLQAQKEVEDAIAALRTSLDALAASSRASDASQ
RALRLANIQYRSGSVTYDSVLDASRSALRDGDSLAQNQGIAALAAVSLYRALGGGWEVAQ
GQQVVSERIAEEMARRTDWGRLLNPPADSALARASANSPPGSK