Protein Info for H281DRAFT_01363 in Paraburkholderia bryophila 376MFSha3.1

Annotation: aerobic C4-dicarboxylate transport protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 433 transmembrane" amino acids 21 to 41 (21 residues), see Phobius details amino acids 57 to 78 (22 residues), see Phobius details amino acids 90 to 112 (23 residues), see Phobius details amino acids 157 to 180 (24 residues), see Phobius details amino acids 193 to 226 (34 residues), see Phobius details amino acids 237 to 260 (24 residues), see Phobius details amino acids 309 to 313 (5 residues), see Phobius details amino acids 319 to 339 (21 residues), see Phobius details amino acids 358 to 388 (31 residues), see Phobius details amino acids 393 to 414 (22 residues), see Phobius details PF00375: SDF" amino acids 22 to 414 (393 residues), 351.1 bits, see alignment E=4.2e-109

Best Hits

Swiss-Prot: 70% identical to DCTA_CUPNJ: C4-dicarboxylate transport protein (dctA) from Cupriavidus necator (strain JMP 134 / LMG 1197)

KEGG orthology group: K11103, aerobic C4-dicarboxylate transport protein (inferred from 95% identity to bgf:BC1003_5361)

MetaCyc: 58% identical to C4 dicarboxylate/orotate:H+ symporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-121; TRANS-RXN-121A; TRANS-RXN-121C; TRANS-RXN-122A; TRANS-RXN0-451; TRANS-RXN0-517; TRANS-RXN0-553

Predicted SEED Role

"C4-dicarboxylate transport protein 1"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MKH5 at UniProt or InterPro

Protein Sequence (433 amino acids)

>H281DRAFT_01363 aerobic C4-dicarboxylate transport protein (Paraburkholderia bryophila 376MFSha3.1)
MSESAVMTSSAPGAKKPFYRTLYFHVFAAIIIGVLLGHFAPSLAVKMKPLGDAFIKLIKM
VIGPIIFCTVVTGIAGMGDMKKVGRVGGKALLYFEIVSTLSLVIGLVAGHIFHPGSGFNL
DPATIDTKALAGYTTAAHQQNTVEFLMHIIPDTVTGAFASGNVLQILLISVLFGAALAAT
GERGRPLIAMIDYFAHTFFGIVHIIMKVAAIGAFGSIAFTIGTYGIGAVVPLLKLIGAFY
ATLAVFVIVVLGAISRLLGFSIFRFMSYIREEILIVLGTSSSEAALPQMLEKLERLGCSK
SVVGLVIPAGYSFNLDGTNIYLTMAVLFIAQAFNIELSLTQQLTLVGVAMLTSKGASGVA
GAAFVMLTSTLLVFPLIPVSGMVLILGIHRFMGTGLAIANTIGNGVATLVVSAWEHELDR
SKLNAGMSRRRAD