Protein Info for H281DRAFT_01330 in Paraburkholderia bryophila 376MFSha3.1

Annotation: pyrroloquinoline quinone biosynthesis protein B

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 306 TIGR02108: coenzyme PQQ biosynthesis protein B" amino acids 2 to 306 (305 residues), 403.1 bits, see alignment E=3.4e-125 PF12706: Lactamase_B_2" amino acids 51 to 273 (223 residues), 154 bits, see alignment E=2.1e-49

Best Hits

Swiss-Prot: 63% identical to PQQB_CUPTR: Coenzyme PQQ synthesis protein B (pqqB) from Cupriavidus taiwanensis (strain DSM 17343 / BCRC 17206 / CIP 107171 / LMG 19424 / R1)

KEGG orthology group: K06136, pyrroloquinoline quinone biosynthesis protein B (inferred from 94% identity to bxe:Bxe_B2467)

Predicted SEED Role

"Coenzyme PQQ synthesis protein B" in subsystem Coenzyme PQQ synthesis or Pyrroloquinoline Quinone biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MKS0 at UniProt or InterPro

Protein Sequence (306 amino acids)

>H281DRAFT_01330 pyrroloquinoline quinone biosynthesis protein B (Paraburkholderia bryophila 376MFSha3.1)
MKIKVLGSSAGGGFPQWNCNCRNCDGVRRGTLKATRRTQSSIAISANGEDWLLVNASPDL
LAQIAANPELQPARRARDSGIAAVLVIDAQIDHVTGLLMLRERDTPLPLYATDAVWQDLT
SGFPIAPMLSHYCGVEHCRIALDGAPLAVDALPGVQIHALPLTSKAPPYSPHRNAPERGD
NIGLVITNRQTGKRVFYAPGLGAIEAHVLDAMREADLLLVDGTLWTADEMIRLGLSKKTA
ADMGHLQQSGPGGMIEVLDSLGEQQVRKVLIHINNTNPILVEDGAERRILMEHGIEVAYD
GMTFEL