Protein Info for H281DRAFT_01247 in Paraburkholderia bryophila 376MFSha3.1

Annotation: esterase, PHB depolymerase family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 367 PF00756: Esterase" amino acids 96 to 228 (133 residues), 41.9 bits, see alignment E=3e-14 PF10503: Esterase_PHB" amino acids 99 to 292 (194 residues), 241.8 bits, see alignment E=1.7e-75 TIGR01840: esterase, PHB depolymerase family" amino acids 101 to 291 (191 residues), 145.8 bits, see alignment E=6.5e-47 PF00326: Peptidase_S9" amino acids 181 to 289 (109 residues), 35.6 bits, see alignment E=2.1e-12

Best Hits

Predicted SEED Role

"Poly(3-hydroxybutyrate) depolymerase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (367 amino acids)

>H281DRAFT_01247 esterase, PHB depolymerase family (Paraburkholderia bryophila 376MFSha3.1)
MKLDEGFLTSMREAMTLLRTRGPAEATEAIQRALGGNAEGSSHGTASWHATPEAFTVPFE
RPAAKHAETVNAREARADIQDRGHFSTHAFSNAAGRRQYRLYVPAESQGEPLPLIVMLHG
CTQNADDFAAGTQMNALAERHRFLVAYPEQPQQANPSKCWNWFKPGDQQCERGEPSLIAG
ITREIIAEQNVDPTRVYVAGLSAGGAMAAIMVAEYPELYAAAGVHSGLPARCAHDLPSAL
AAMKGGKRPVQARRGAHGTASLPKRPVIVFHGDADATVNIRNAAQLVDGFSARPQGDGEQ
RRTDAGGRACTVSRLVSADGIDAELWTIHGAPHAWAGGNARGSYTDPAGPDASAEMLRFF
LEHPQRR