Protein Info for H281DRAFT_01211 in Paraburkholderia bryophila 376MFSha3.1

Annotation: Transcriptional regulator of acetoin/glycerol metabolism

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 658 PF01590: GAF" amino acids 62 to 190 (129 residues), 50.9 bits, see alignment E=6.1e-17 PF00158: Sigma54_activat" amino acids 335 to 497 (163 residues), 217.3 bits, see alignment E=2.7e-68 PF14532: Sigma54_activ_2" amino acids 337 to 503 (167 residues), 73.3 bits, see alignment E=6.1e-24 PF07728: AAA_5" amino acids 355 to 467 (113 residues), 26.1 bits, see alignment E=1.9e-09 PF02954: HTH_8" amino acids 618 to 653 (36 residues), 32.2 bits, see alignment 1.8e-11

Best Hits

KEGG orthology group: None (inferred from 87% identity to bug:BC1001_3842)

Predicted SEED Role

"Nitrogen regulation protein NR(I)" in subsystem Ammonia assimilation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MJ14 at UniProt or InterPro

Protein Sequence (658 amino acids)

>H281DRAFT_01211 Transcriptional regulator of acetoin/glycerol metabolism (Paraburkholderia bryophila 376MFSha3.1)
LTHRTATPPTVGRPDVIAQAHARSVELGLRASETPDFHPLNRLALRELVDRNQSLYTHAL
PVMETLHAQIVDTQSMVLLTDSRGVILHSLGDSDFVEKANRVALCPGVSWAEADRGTNAI
GTALVDAQPTVVHADEHFLHANRILTCSCAPIADPFGHTIGALDVSGDTRGFHKHTLALV
RMSAQMIENHLFSNQFADAVRVHFHARAEFIGTLFEGLAAFGADGTFLSANRSALFQFGQ
PLAALQRQPFHALFGVPFAHVLQQIARAPGENTVLTLPSGVRVVARGEYSAQRYVTPSIG
ETEGSRGVASKSARGVPHTADPAPLATLETLDTGDAKVAAILARVAKVRGRDIPILILGK
TGTGKEWLARAIHHDSPRRAAPFVALNCASLPDTLIEAELFGYEDGAFTGAKKRGSVGKI
VQADGGTLFLDEIGDMPLAQQVRLMRVLQERTVLPLGGTRAIPVDLRIVCATHRNLRAMI
AEGTFREDLYYRINGLVVTLPALRERTDLAALVERMLELQPEADGLPRRVSAAVLERFMQ
CRWPGNLRQLANVLRTASIMAEGTDQIELDDLPEDFLHDCDDEAADENAPSTLKAVDDAT
GDAGSAHSPQPSRMDDWQAALIAQTLARLDGNVSAAARELGLARNTVYRYLRRGGATH