Protein Info for H281DRAFT_01190 in Paraburkholderia bryophila 376MFSha3.1

Annotation: NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 422 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF03486: HI0933_like" amino acids 3 to 41 (39 residues), 26 bits, see alignment 9.8e-10 PF07992: Pyr_redox_2" amino acids 3 to 294 (292 residues), 112.4 bits, see alignment E=7e-36 PF12831: FAD_oxidored" amino acids 4 to 43 (40 residues), 30.1 bits, see alignment 8.3e-11

Best Hits

KEGG orthology group: None (inferred from 55% identity to bte:BTH_II2064)

Predicted SEED Role

"Putative oxidoreductase in 4-hydroxyproline catabolic gene cluster" in subsystem Proline, 4-hydroxyproline uptake and utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MQF9 at UniProt or InterPro

Protein Sequence (422 amino acids)

>H281DRAFT_01190 NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase (Paraburkholderia bryophila 376MFSha3.1)
MNFDILIIGAGPAGLHAASVAAQAGATVGIVDDNALPGGQIWRQGPHHRPQGRGREAIDA
VAQAANVARLHGTRVVQALREHELLVEDATRGYAIGYDKLIIATGARERFLPYPGWTLPG
VTGAGGLQALVKGGMPVRGERVVIAGTGPLLWAAAVTAREQGAHVAAIVEQAPTHAVRQF
AMSLVSTPAKLAQAARMRFALRATPYLRGAYVSAAHGDQKITQVVVQQGTRQTQIDCDRL
ACAYGLVPNTIPGTALGCDVAETDGVLALVVDDFQATTQPGIYAAGECTGVGGMELSAVE
GRIAALAAIGNVADARALFAERERYRRFAAKMHTAFALDPQLRGLATADTVMCRCEDVSF
GEVAQHRGWRDAKLHTRCGMGPCQGKICGEAAAFCLGWSRYGQRPPFSPARVSTLMSFQT
PV