Protein Info for H281DRAFT_01185 in Paraburkholderia bryophila 376MFSha3.1

Annotation: MFS transporter, AAHS family, 4-hydroxybenzoate transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 453 transmembrane" amino acids 21 to 44 (24 residues), see Phobius details amino acids 59 to 80 (22 residues), see Phobius details amino acids 87 to 107 (21 residues), see Phobius details amino acids 115 to 134 (20 residues), see Phobius details amino acids 146 to 165 (20 residues), see Phobius details amino acids 177 to 196 (20 residues), see Phobius details amino acids 259 to 279 (21 residues), see Phobius details amino acids 299 to 315 (17 residues), see Phobius details amino acids 323 to 342 (20 residues), see Phobius details amino acids 348 to 370 (23 residues), see Phobius details amino acids 383 to 408 (26 residues), see Phobius details amino acids 414 to 434 (21 residues), see Phobius details PF07690: MFS_1" amino acids 26 to 285 (260 residues), 113.7 bits, see alignment E=9.6e-37 amino acids 261 to 427 (167 residues), 37.1 bits, see alignment E=1.9e-13 PF00083: Sugar_tr" amino acids 55 to 430 (376 residues), 83.3 bits, see alignment E=1.8e-27

Best Hits

Predicted SEED Role

"4-hydroxybenzoate transporter" in subsystem Cinnamic Acid Degradation or Gentisare degradation or Phenylpropanoid compound degradation or Salicylate and gentisate catabolism or p-Hydroxybenzoate degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (453 amino acids)

>H281DRAFT_01185 MFS transporter, AAHS family, 4-hydroxybenzoate transporter (Paraburkholderia bryophila 376MFSha3.1)
MKTIDVKSFIDQRPLKPFHAILFMLMFLTIVLDGLDTSAMGLIAPTLMKQWGVTKSDLAP
VLSAALVGIGIGAIFGAPLADRIGRRVVLVTSVAFFGVFSIAAGCSTNVTELMWSRLLTG
VGLGAAIPLCATLVNEFLPSRMRSRAVNFMLFGFAVGGGITGPLAKSVIPTHGWEGYLIV
GGVAPIVVAVLLAFFLPESVRYLAAAGKGQDKIVKALKRIDPTADFTDTTFVAEVSAAVQ
KRKFPVSELFSARLRWPTMLLWVAYICSTITLYVLSMWLPTILQGDGRTLAQTANTMMWF
NWCSGAAILLAGVLMDKFGPVRVISAYFAISMSMALLVSISGAHGDALLTLLVIAAMTNN
GACSSMSTLATQMYPTSSRATGAAWVLGVGRFGGIAGTFLGPVMIGLGWPLTTIVAWIAL
PAVIASVSIFCIGFRIPALRRGYVGLPSGEAVH