Protein Info for H281DRAFT_01174 in Paraburkholderia bryophila 376MFSha3.1

Annotation: Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 353 signal peptide" amino acids 1 to 16 (16 residues), see Phobius details PF00296: Bac_luciferase" amino acids 1 to 302 (302 residues), 205.9 bits, see alignment E=5.1e-65

Best Hits

Swiss-Prot: 56% identical to Y4VJ_SINFN: Uncharacterized protein y4vJ (NGR_a01140) from Sinorhizobium fredii (strain NBRC 101917 / NGR234)

KEGG orthology group: None (inferred from 64% identity to bja:bll3440)

Predicted SEED Role

"putative LuxA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (353 amino acids)

>H281DRAFT_01174 Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase) (Paraburkholderia bryophila 376MFSha3.1)
MEFGVFLLAQQRSYAQTSQSVIHNTIEQTVVAEQAGFDAAWYAEHHFNNYSLSPSPLMTI
AHAAAKTTKIRLGSAVCILPLYHPARLLTEVGLADTLSDGRLELGIGSGYQQFEFERFGC
NLANSGEIFHEVWDILNKGLNEKVFEYKGKHFDMLPTSVAVRTVQKKIPFWITSMNPSTL
GRAFSENVNLFTTVLHGGNDALRALRDRLEGLAAQLGKDLGQTKIGFLRCGFASDSKAEV
DAYLDSARWARRISEALKDRRMDVDDGYLMKETPCAADMTLDQLRQNLPVGSVNQVIDKL
LAEIEILKPNHIALQTQLGDCDQKTMLRQIELWGDKIIPAVRKELARNNKLAA