Protein Info for H281DRAFT_01157 in Paraburkholderia bryophila 376MFSha3.1

Annotation: 2-keto-3-deoxygluconate permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 338 transmembrane" amino acids 12 to 29 (18 residues), see Phobius details amino acids 42 to 63 (22 residues), see Phobius details amino acids 76 to 97 (22 residues), see Phobius details amino acids 104 to 129 (26 residues), see Phobius details amino acids 141 to 164 (24 residues), see Phobius details amino acids 170 to 187 (18 residues), see Phobius details amino acids 194 to 214 (21 residues), see Phobius details amino acids 224 to 243 (20 residues), see Phobius details amino acids 255 to 274 (20 residues), see Phobius details amino acids 286 to 310 (25 residues), see Phobius details TIGR00793: 2-keto-3-deoxygluconate transporter" amino acids 1 to 312 (312 residues), 496 bits, see alignment E=2.7e-153 PF03812: KdgT" amino acids 4 to 312 (309 residues), 372.4 bits, see alignment E=1e-115

Best Hits

Swiss-Prot: 70% identical to KDGT_SHIFL: 2-keto-3-deoxygluconate permease (kdgT) from Shigella flexneri

KEGG orthology group: K02526, 2-keto-3-deoxygluconate permease (inferred from 96% identity to bug:BC1001_1557)

MetaCyc: 70% identical to 2-dehydro-3-deoxy-D-gluconate:H+ symporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-113

Predicted SEED Role

"2-keto-3-deoxygluconate permease (KDG permease)" in subsystem D-Galacturonate and D-Glucuronate Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MC69 at UniProt or InterPro

Protein Sequence (338 amino acids)

>H281DRAFT_01157 2-keto-3-deoxygluconate permease (Paraburkholderia bryophila 376MFSha3.1)
MKLKKAIDRIPGGLMLVPLLLGACVHTFAPGAGKYFGSFTNGLIAGTVPILAVWFFCMGA
TIDLRATGTVLRKSGTLLVTKMVVAWIATLVASHFIPIDGIKGGLFAGLSVLAITTSMDM
TNGGLYAAVMQQYGTKEEAGAFVLMSVESGPLVSMIILGATGVAFFEPRLFVGAVLPFLI
GFALGNIDSDLREFFGRCVHPLIPFFGFALGNGIDLNVIAKSGMAGVLLGLAVIVVTGIP
LILADRWIAGGNGAAGLAASSTAGAAVANPAIIGEMIPSFKPLVPAATAMVATACLVTAI
LVPMLTALWVRRHHARDTLREELLAPAAPPLKESDMHV