Protein Info for H281DRAFT_01149 in Paraburkholderia bryophila 376MFSha3.1

Annotation: two-component system, OmpR family, sensor histidine kinase QseC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 502 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details transmembrane" amino acids 175 to 197 (23 residues), see Phobius details PF00512: HisKA" amino acids 246 to 307 (62 residues), 46.5 bits, see alignment E=3.1e-16 PF02518: HATPase_c" amino acids 416 to 489 (74 residues), 46.7 bits, see alignment E=4e-16

Best Hits

Predicted SEED Role

"Sensory histidine kinase QseC" in subsystem Orphan regulatory proteins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (502 amino acids)

>H281DRAFT_01149 two-component system, OmpR family, sensor histidine kinase QseC (Paraburkholderia bryophila 376MFSha3.1)
MSASIRRRLMLLVLASIGLVWAIALASSYRQATREVAEWEEARLAEVAQMLALLDQSNLA
TLANAHIDVREEERGGETSANDTDDDDSLPRDALFQVRARNGDVIAGSPPLRALNAWDLP
VPPVTGVQDVVLGGQTYHSFTLRDTPLGHTVRVFEQANTRSDLVSGVASRIARPALIALP
VLALLVWWSIGWSLAPLRMLSDAIRSRDINRLEPVDIGHVPIEVRPLVDAINLLLSRLLH
SLERERAFTADAAHELKTPLAAIKVQAQVALAEPDPARQRLAMERVVQGVDRSARLAEQL
LLLARLDMQEKMATAPLAPGAVAKSALLANAGNAQQKNIRVTLNCDMRAEINAEPVLIGI
LFDNLLDNAIKYGSDGGTIEIAVRREKQHVPAPLKEPLKEPLQEPAKGPAKEPLSERILV
SVRDDGPGVAPADLARLTDRFFRATGNQATGSGLGLSIVARIAQHFGATVRFGTGLDGRG
LAVDVSFPAYTAASVRSLKPVG