Protein Info for H281DRAFT_01140 in Paraburkholderia bryophila 376MFSha3.1

Annotation: 2-furoyl-CoA dehydrogenase FAD binding subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00941: FAD_binding_5
  • amino acids 5 to 176 (172 residues), 140.2 bits, E=6e-45

Best Hits

KEGG orthology group: K03519, carbon-monoxide dehydrogenase medium subunit [EC: 1.2.99.2] (inferred from 90% identity to bpy:Bphyt_2184)

MetaCyc: 81% identical to hmfB (Cupriavidus basilensis)
2-furoyl-CoA dehydrogenase. [EC: 1.3.99.8]

Predicted SEED Role

"Carbon monoxide dehydrogenase medium chain (EC 1.2.99.2)" in subsystem CO Dehydrogenase (EC 1.2.99.2)

MetaCyc Pathways

• furfural degradation (6/8 steps found)
• 5-hydroxymethylfurfural degradation (6/10 steps found)

KEGG Metabolic Maps

• Methane metabolism
• Trinitrotoluene degradation

Isozymes

Compare fitness of predicted isozymes for: 1.2.99.2

Use Curated BLAST to search for 1.2.99.2 or 1.3.99.8

Sequence Analysis Tools

See A0A2Z5MAR9 at UniProt or InterPro

Protein Sequence (273 amino acids)

>H281DRAFT_01140 2-furoyl-CoA dehydrogenase FAD binding subunit (Paraburkholderia bryophila 376MFSha3.1)
MKPAPFDYLRAMNAQHALDALAQHGEDARVLAGGQSLMAVLNMRLAQPRMLIDISRTGEL
DSVRVDRKAGSLTVGAAATQGSVEWRASLRDEVPLLAMAFPHISHFQIRNRGTVCGSIAH
ADPSAELPLVLSALGGDVMLRSKKKPRVLSADAFFQGMLMTAREPDELVEAVRFPLKREG
ERYGFAEFSARHGDFAIVACAAVVTDDAIRLAVGGVADRPVVEQWPRLSGDDLRGALNDL
SWKLGAQDNAHISASYRRHLVRQLGWRVIEEAK