Protein Info for H281DRAFT_01118 in Paraburkholderia bryophila 376MFSha3.1

Annotation: deoxyribose-phosphate aldolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00126: deoxyribose-phosphate aldolase
  • amino acids 72 to 295 (224 residues), 135 bits, E=1.2e-43
• PF01791: DeoC
  • amino acids 73 to 285 (213 residues), 83.2 bits, E=1.1e-27

Best Hits

Swiss-Prot: 60% identical to DEOC_HUMAN: Deoxyribose-phosphate aldolase (DERA) from Homo sapiens

KEGG orthology group: K01619, deoxyribose-phosphate aldolase [EC: 4.1.2.4] (inferred from 95% identity to bug:BC1001_1577)

Predicted SEED Role

"Deoxyribose-phosphate aldolase (EC 4.1.2.4)" in subsystem Deoxyribose and Deoxynucleoside Catabolism (EC 4.1.2.4)

MetaCyc Pathways

• 2-deoxy-D-ribose degradation I (3/3 steps found)
• 2-deoxy-α-D-ribose 1-phosphate degradation (2/3 steps found)
• superpathway of pyrimidine deoxyribonucleosides degradation (3/6 steps found)
• superpathway of purine deoxyribonucleosides degradation (3/7 steps found)

KEGG Metabolic Maps

• Pentose phosphate pathway

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.1.2.4

Protein Sequence (337 amino acids)

>H281DRAFT_01118 deoxyribose-phosphate aldolase (Paraburkholderia bryophila 376MFSha3.1)
MPDPSFSPSSSVVALRGGPLVHPVRNPGMPFDASWLDGLRINQSAVERRTATLATRRTVK
KDAQAAWLLKAVTCIDLTTLSGDDTEGRVRRLCAKARQPVRADLLEALGMTPQRVTTGAV
CVYHRFVAAAVDALKGSGIPVAAVSTGFPAGLIPHPLKLKEIEASVADGAAEIDIVVTRE
YVLTGNWQALYDEVREFRAACGPAHLKAILATGDIRTLSNIARASMVCMMAGADFIKTST
GKEGVNATLDVSLVMVRMIREYHERTGVPIGFKPAGGVSSAKSVLSYQILMKEELGRAWL
EPELFRIGASSLLADIERQLEHHVSGRYSAFNRHPVA