Protein Info for H281DRAFT_01112 in Paraburkholderia bryophila 376MFSha3.1

Updated annotation (from data): deoxynucleoside transporter, permease component 2
Rationale: Important for utilization of dAMP and deoxyinosine. Because the fitness profiles for these compounds are very similar, dAMP is likely hydrolyzed before uptake, but this could also be a transporter for deoxynucleotides.
Original annotation: monosaccharide ABC transporter membrane protein, CUT2 family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 364 transmembrane" amino acids 52 to 69 (18 residues), see Phobius details amino acids 81 to 100 (20 residues), see Phobius details amino acids 106 to 127 (22 residues), see Phobius details amino acids 132 to 154 (23 residues), see Phobius details amino acids 170 to 189 (20 residues), see Phobius details amino acids 210 to 231 (22 residues), see Phobius details amino acids 259 to 280 (22 residues), see Phobius details amino acids 290 to 307 (18 residues), see Phobius details amino acids 316 to 336 (21 residues), see Phobius details amino acids 342 to 360 (19 residues), see Phobius details PF02653: BPD_transp_2" amino acids 78 to 354 (277 residues), 126.8 bits, see alignment E=4.7e-41

Best Hits

KEGG orthology group: K02057, simple sugar transport system permease protein (inferred from 93% identity to bug:BC1001_1583)

Predicted SEED Role

"Ribose ABC transport system, permease protein RbsC (TC 3.A.1.2.1)" in subsystem D-ribose utilization (TC 3.A.1.2.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MAN5 at UniProt or InterPro

Protein Sequence (364 amino acids)

>H281DRAFT_01112 deoxynucleoside transporter, permease component 2 (Paraburkholderia bryophila 376MFSha3.1)
MNSRIPSRTDPRTDPPSASPMKQTMTTPTVVEIAPSVEAPGLRTRLARNPEWFTVALIVV
TCLIVGAINPRFFQFATLFDLLHSATTMSLFALGTLVVLASGGIDVSFTAIAALTMYGIT
KAVFAWWPDAPFALILVTGALGGVVLGMVNGLLVHRLKAPSLIVTIGTQYLYRGLLLTFI
GTTFFMNIPHSMDRFGRIPLFFYHTADGLRAVLPVSVLALVAAAVVTWWLLNRTMMGRAV
YAMGGSLAIAERLGYNLRAIHLFVFGYTGMLAGIAGILHVSNNRLANPFDLVGSELDVIA
AVILGGARITGGTGTVVGTLLGVVLVTLIKSVLILVGVPSTWQKVIIGAFILLAGTLFAL
QRKR