Protein Info for H281DRAFT_01064 in Paraburkholderia bryophila 376MFSha3.1

Annotation: Tetratricopeptide (TPR) repeat

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 520 PF14559: TPR_19" amino acids 14 to 65 (52 residues), 29.5 bits, see alignment 5.4e-10 amino acids 84 to 142 (59 residues), 28.7 bits, see alignment 9.6e-10 PF13432: TPR_16" amino acids 16 to 60 (45 residues), 28.3 bits, see alignment 1.4e-09 amino acids 85 to 126 (42 residues), 16 bits, see alignment 1e-05 amino acids 112 to 170 (59 residues), 22.3 bits, see alignment 1.1e-07 amino acids 143 to 206 (64 residues), 32.9 bits, see alignment E=5.2e-11 amino acids 178 to 223 (46 residues), 17.7 bits, see alignment 3e-06 PF13174: TPR_6" amino acids 81 to 104 (24 residues), 14.8 bits, see alignment (E = 2.6e-05) PF13181: TPR_8" amino acids 139 to 170 (32 residues), 19.4 bits, see alignment (E = 6.3e-07) amino acids 173 to 206 (34 residues), 26.3 bits, see alignment (E = 3.7e-09) PF07719: TPR_2" amino acids 174 to 206 (33 residues), 31 bits, see alignment (E = 1.1e-10) PF00515: TPR_1" amino acids 174 to 206 (33 residues), 34.1 bits, see alignment (E = 1.2e-11) PF13374: TPR_10" amino acids 175 to 201 (27 residues), 18.2 bits, see alignment (E = 1.4e-06) PF01075: Glyco_transf_9" amino acids 434 to 467 (34 residues), 30 bits, see alignment (E = 2.3e-10)

Best Hits

KEGG orthology group: None (inferred from 67% identity to bph:Bphy_4648)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (520 amino acids)

>H281DRAFT_01064 Tetratricopeptide (TPR) repeat (Paraburkholderia bryophila 376MFSha3.1)
MHIEHALAAAQKNLMAGQLDDAASLLHGILASVPDHSEALSGLGYIAAEQGDHARAAEFL
IQASAHMSVSFEQLNFAARVCQLAQRHDDAIALFERCLARFPDHAASLHGVAMELIQLGE
LQRALEILVHLCKIQPQSAEAHYNRGSLLGKLERYEDELDAYRQAIALKPRFVRAYVNLG
VALRDLRRFDEALLQFKKALSLDPNDVGARTNRAQTNLLLGEFEHGWREYEWRWRDGTGS
HGFPQSTLWTGGQPIRDRTILVHHEQGFGDTLQFVRFVDRLSAAGARVVLRVQDALLPLL
KNYRGAAEVIGETGEVPHFDYHIPTLSLPFALKVRAPDLAVTGPYVHADDALVRQWDDLF
AASARRPKVGIVWSGSRTHVNDHNRSISLEQLTPLFDADADFFALQHDVRDSDRTCLAQL
EQRALLRDVSAQLTTFAETAALIARLDLVISVDTAVAHLAGALGKPVWIAVPFMPDWRWQ
LDRSDSPWYAQAHLFRQTTRGDWTGVVAALRAELDAWRGA