Protein Info for H281DRAFT_01057 in Paraburkholderia bryophila 376MFSha3.1

Annotation: monosaccharide ABC transporter ATP-binding protein, CUT2 family (TC 3.A.1.2.-)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 517 PF00005: ABC_tran" amino acids 28 to 178 (151 residues), 117.2 bits, see alignment E=9e-38 amino acids 281 to 433 (153 residues), 66.7 bits, see alignment E=3.5e-22

Best Hits

Swiss-Prot: 46% identical to RGMG1_RHIME: Putative ribose/galactose/methyl galactoside import ATP-binding protein 1 (R02565) from Rhizobium meliloti (strain 1021)

KEGG orthology group: K10441, ribose transport system ATP-binding protein [EC: 3.6.3.17] (inferred from 48% identity to spe:Spro_1029)

Predicted SEED Role

"Ribose ABC transport system, ATP-binding protein RbsA (TC 3.A.1.2.1)" in subsystem D-ribose utilization (TC 3.A.1.2.1)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.17

Use Curated BLAST to search for 3.6.3.17

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (517 amino acids)

>H281DRAFT_01057 monosaccharide ABC transporter ATP-binding protein, CUT2 family (TC 3.A.1.2.-) (Paraburkholderia bryophila 376MFSha3.1)
MNGHADISAGDLLEVIRITKEFPGVKSLDQVSLGVRAGEIHALVGENGAGKSTLTKIMAG
VYAPDSGEIRFAGQPLQWKSAADAKRHGIHVIHQELVLFPQSTVAENIFAGAEPRTRIGV
LDHGRMNRDAQALLGELGVRLDSRERVGNLSVADQQMVEIAKAMAGETRVLILDEPTAVI
AGKEVQLLFARVRALRAKGVAIVYISHRLDEIFELCDRVTVMKDGRKVATQSVANTTRDQ
LVRLMVGREMKDIYPDKPILAPGVPNVLEVNGLCVGNRVVDASLTVRAGEIVGIAGMVGS
GRTELAAGIFGALRAHRGTVDIGGTRRTRMTPRTAIRLGLGFVTEDRKSQGLLMLLDVAQ
NVTATTLAQVSRFGLMRPALERAAAQAAINEYRIAGAHPAGGVATLSGGNQQKVLISRWV
RVCKRVLILDEPTRGVDVGAKAEIYRVMRELTSRGLGILMISSELQEVIGMSDRVLVMRE
GRINGEVSGEQMTEHDIMRLATTETSQTTGDAHEHAY