Protein Info for H281DRAFT_00997 in Paraburkholderia bryophila 376MFSha3.1

Annotation: amino acid/amide ABC transporter substrate-binding protein, HAAT family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 383 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details PF13433: Peripla_BP_5" amino acids 31 to 354 (324 residues), 53.4 bits, see alignment E=3.4e-18 PF13458: Peripla_BP_6" amino acids 31 to 369 (339 residues), 213.1 bits, see alignment E=1.4e-66 PF01094: ANF_receptor" amino acids 51 to 369 (319 residues), 79.8 bits, see alignment E=3e-26

Best Hits

KEGG orthology group: K01999, branched-chain amino acid transport system substrate-binding protein (inferred from 87% identity to bph:Bphy_6859)

Predicted SEED Role

"Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (383 amino acids)

>H281DRAFT_00997 amino acid/amide ABC transporter substrate-binding protein, HAAT family (Paraburkholderia bryophila 376MFSha3.1)
MLDRSRKFFIFALSAIVLTLASHVCSAQQVVKIGVSAPLTGNGAANGKDIENGVRLALEE
ANAQRIKLGGQEVRFELDSVDDQGDPRIGVQVAQKLVDDGVVAVVGYYNSGVALPSAPIF
AKAGIPLIDPAATNPAITRQGLKNVFRIIATDAQNSGNAGKYAVNVTKAQRIAVMDDRTA
FGQGAADEFKKAVQGAGGKIVASEFTNDKAVEFNAQLTTIKAANADLLYFAGLNNQAALV
TKRMKQLGMRAQFVGSGGIADSIFISVAGTAAEGAMAWEYGRPVESLPQGRAFAEKFKKR
FGANTLTYAPFAYDCAWVAIDAMKQANSAKPDVFMPVLHATKYDGITGKIEFDEFGDLKR
PTSTLYQVKNAKWVPVTTISPPN