Protein Info for H281DRAFT_00929 in Paraburkholderia bryophila 376MFSha3.1

Annotation: DNA polymerase III, delta prime subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 344 TIGR00678: DNA polymerase III, delta' subunit" amino acids 16 to 223 (208 residues), 205.2 bits, see alignment E=3.4e-65 PF13177: DNA_pol3_delta2" amino acids 17 to 188 (172 residues), 136.6 bits, see alignment E=4.2e-44

Best Hits

KEGG orthology group: K02341, DNA polymerase III subunit delta' [EC: 2.7.7.7] (inferred from 94% identity to bug:BC1001_1674)

Predicted SEED Role

"DNA polymerase III delta prime subunit (EC 2.7.7.7)" in subsystem DNA-replication (EC 2.7.7.7)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.7

Use Curated BLAST to search for 2.7.7.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MCT1 at UniProt or InterPro

Protein Sequence (344 amino acids)

>H281DRAFT_00929 DNA polymerase III, delta prime subunit (Paraburkholderia bryophila 376MFSha3.1)
MIYPWQADDWNRLQQLRDHWPHALLLHGQAGIGKLRFAQHLAQGLLCEDQRDNGEPCGAC
VACNWFTQGNHPDYRIVVPEALAAEAGIGNGADEKAEKADGDEGKKTRSPSKEIKIEQIR
GLLDFVGVGSHRGGARVVVLAPAEALNIAAANALLKTLEEPPAGVVFLMVSARIDRLLPT
IISRCRQWPMSLPAPQAATQWLAGQGLAEAPALLAEAGGAPLTALALASDENRTLRDWTL
KQLAAGPQCDAFACGEALQKLPVPLVLGWLQRWMYDLLAQRTAGAPRYFPQASAALTRCA
SQADASAFARFMRAVTRQRAVENHPLNARLVFEELFLGYRELFA