Protein Info for H281DRAFT_00902 in Paraburkholderia bryophila 376MFSha3.1

Annotation: peptidyl-prolyl cis-trans isomerase D

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 645 transmembrane" amino acids 12 to 32 (21 residues), see Phobius details PF13624: SurA_N_3" amino acids 1 to 166 (166 residues), 150.4 bits, see alignment E=1e-47 PF13623: SurA_N_2" amino acids 2 to 143 (142 residues), 86.6 bits, see alignment E=3.9e-28 PF13145: Rotamase_2" amino acids 250 to 388 (139 residues), 94.4 bits, see alignment E=2.3e-30 PF13616: Rotamase_3" amino acids 268 to 376 (109 residues), 109.5 bits, see alignment E=3.7e-35 PF00639: Rotamase" amino acids 276 to 374 (99 residues), 100.3 bits, see alignment E=2.5e-32

Best Hits

KEGG orthology group: K03770, peptidyl-prolyl cis-trans isomerase D [EC: 5.2.1.8] (inferred from 94% identity to bpy:Bphyt_1910)

Predicted SEED Role

"Peptidyl-prolyl cis-trans isomerase PpiD (EC 5.2.1.8)" (EC 5.2.1.8)

Isozymes

Compare fitness of predicted isozymes for: 5.2.1.8

Use Curated BLAST to search for 5.2.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MB45 at UniProt or InterPro

Protein Sequence (645 amino acids)

>H281DRAFT_00902 peptidyl-prolyl cis-trans isomerase D (Paraburkholderia bryophila 376MFSha3.1)
MLDFFRNHKRLMMFMLILVIVPGLGFVGIQGFRGFFDESANVASVNGHKITRAEYDNAMR
QQLDRARQMLGAQFDMKAFDTPQRRSEMLDGLIEQRVLADETQRLHLTASDDAVRRTLLN
DPVISSLKNPDGSIDVDRYKQLLAMQGMTPDQYDERVRYSIATQQLPASIQGSAFTSKTL
AQHLTELAEQQREVQGIAFHPRDYAAKVQPTDAQLQAYYDAHRNEFATPATATIQYLVMS
PATLAASVQPSDADLKKYYDDNIAHYRTEGQVRASHILITAPKDASAADKAKAKQKAEEL
LAQIKAHPEQFAQIAQQNSQDPGSASKGGDLGYFGRGMIAGGQAFDDAVFALKKDEVSGI
VQTDFGYHIVKVTDVKPAVTKPFDEVKDQISRDLKTQLASKAFSDDSEGFTSIVYEKAKS
LQPAADKYKLQLQTATVTPQPDPKLPPDSPLNNAKFLAAVFANDAAVARNNTQAIDVGSN
TLIAARVTDYKAAAVPALDAIKDLVRQKVIAAQSNEAAHKDGIAKLAEFEKSKATTGFSS
PLKVSRNDAQGVPPAALSAIYKADAQKLPAYVGVDLGDDGYAIYRVNSVVAGTPVEPQRL
AAAQQQIAQVESQSEVETYVQALRARSKVKLYGSLESSNAQASDE