Protein Info for H281DRAFT_00860 in Paraburkholderia bryophila 376MFSha3.1

Annotation: phosphoserine phosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 279 PF13284: DUF4072" amino acids 3 to 49 (47 residues), 57.8 bits, see alignment 2.9e-19 TIGR00338: phosphoserine phosphatase SerB" amino acids 69 to 277 (209 residues), 225.7 bits, see alignment E=5.1e-71 TIGR01488: HAD phosphoserine phosphatase-like hydrolase, family IB" amino acids 74 to 246 (173 residues), 101.7 bits, see alignment E=4.7e-33 PF00702: Hydrolase" amino acids 74 to 248 (175 residues), 76.3 bits, see alignment E=1.1e-24 PF12710: HAD" amino acids 76 to 244 (169 residues), 79.3 bits, see alignment E=1.4e-25 PF08282: Hydrolase_3" amino acids 200 to 274 (75 residues), 42.7 bits, see alignment E=1.5e-14

Best Hits

KEGG orthology group: K01079, phosphoserine phosphatase [EC: 3.1.3.3] (inferred from 92% identity to bgf:BC1003_1565)

Predicted SEED Role

"Phosphoserine phosphatase (EC 3.1.3.3)" in subsystem Glycine and Serine Utilization or Serine Biosynthesis (EC 3.1.3.3)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.1.3.3

Use Curated BLAST to search for 3.1.3.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MA89 at UniProt or InterPro

Protein Sequence (279 amino acids)

>H281DRAFT_00860 phosphoserine phosphatase (Paraburkholderia bryophila 376MFSha3.1)
MNLVIQSPAPISTDHHKTLVALSRGSHATVVDANAIRISDADIAQRPDLDVYCGTHRLDY
AFVEAGRQLRDFGLVAMDMDSTLITIECIDEIADFCGLKAEVAAITEASMRGEIKDFNES
LTRRVALLKGLDASALERVYEERLQLSPGAEQMLAGAKEAGLKTLLVSGGFNFFTEKLKA
RLGLDFTRANTLDIVDGKLTGKVIGEIVNADVKARTLRETCAQLGIEPSRAIAMGDGSND
LKMMAEAGLSVAFRAKPVVREAASVAFNYVGLDGLLRLF