Protein Info for H281DRAFT_00839 in Paraburkholderia bryophila 376MFSha3.1

Annotation: NADPH2:quinone reductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 324 PF08240: ADH_N" amino acids 28 to 87 (60 residues), 43.9 bits, see alignment E=2.8e-15 PF00107: ADH_zinc_N" amino acids 151 to 270 (120 residues), 104.5 bits, see alignment E=6.4e-34 PF13602: ADH_zinc_N_2" amino acids 184 to 322 (139 residues), 73.9 bits, see alignment E=3.9e-24

Best Hits

Swiss-Prot: 40% identical to QORL2_NEMVE: Quinone oxidoreductase-like protein 2 homolog (v1g238856) from Nematostella vectensis

KEGG orthology group: None (inferred from 90% identity to bug:BC1001_1802)

Predicted SEED Role

"Quinone oxidoreductase (EC 1.6.5.5)" in subsystem ZZ gjo need homes (EC 1.6.5.5)

Isozymes

Compare fitness of predicted isozymes for: 1.6.5.5

Use Curated BLAST to search for 1.6.5.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (324 amino acids)

>H281DRAFT_00839 NADPH2:quinone reductase (Paraburkholderia bryophila 376MFSha3.1)
MRAIRCNQYGPPETLTVENLPELLPEAGQVVIDVKAASVNFPDVLIIENKYQFKPPLPFT
PGSEVAGIVRAVGAGVTQLTSGSRVVAFTGSGGFAEQAVASASACVPLADGVDFELAAAF
TLAYGTSHHAVVDRAALQAGETMLVLGAAGGVGLAAVEIGKALGARVIAAASSDEKLSIC
KKHGADATINYSTEDLRERIKALTDGRGPDVIYDPVGGVYTEPAFRSIGWRGRYLVVGFA
NGEIPKLPLNLTLLKGASVVGVFWGDFAKREPERNHAAFEQMVGWIGEGKLEPYVSARYP
LEETGRALRDMAERRVIGKVVITP